PIP5K1C
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Official Full Name
phosphatidylinositol-4-phosphate 5-kinase, type I, gamma -
Overview
Phosphatidylinositol-4-phosphate 5-kinases (PIP5K) synthesize phosphatidylinositol-4,5-bisphosphate (PtdInsP2), a key precursor in phosphoinositide signaling that also regulates some proteins and cellular processes directly. There are two subfamilies of P -
Synonyms
PIP5K1C;phosphatidylinositol-4-phosphate 5-kinase, type I, gamma;phosphatidylinositol-4-phosphate 5-kinase type-1 gamma;KIAA0589;LCCS3;PIP5Kgamma;PIP5K1-gamma;type I PIP kinase;diphosphoinositide kinase;ptdIns(4)P-5-kinase 1 gamma;Human homolog
Recombinant Proteins
- Human
- Mouse
- E.coli
- Sf9 Cells
- Insect Cells
- Sf21 Cells
- Mammalian Cells
- HEK293
- His
- GST
- Non
- DDK
- Myc
- Avi
- Fc
Involved Pathway
PIP5K1C involved in several pathways and played different roles in them. We selected most pathways PIP5K1C participated on our site, such as Inositol phosphate metabolism,Metabolic pathways,Phosphatidylinositol signaling system, which may be useful for your reference. Also, other proteins which involved in the same pathway with PIP5K1C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Endocytosis | GRK7B,ACAP3,RHOAA,EPN1,HSPA1L,TGFB1A,RHOA,BIN1B,SH3GLB2A,IL2RB |
| Choline metabolism in cancer | AKT1,PIK3CG,PIP5K1A,MAPK1,RAC2,PPAP2C,PIK3R2,PLA2G4C,WASF1,PDGFRB |
| Fc gamma R-mediated phagocytosis | VAV3,PLD1,ARPC1A,CFL1,PAK1,VAV2,INPP5D,PIK3CD,RAC1,RAF1 |
| Inositol phosphate metabolism | ITPKC,MIOX,MTMR1B,PTENA,INPP5K,IPMK,PI4KB,MTMR2,INPP1,TPI1A |
| Phosphatidylinositol signaling system | PIK3C3,PI4KA,IP6K1,PIP5K1AB,PIK3C2B,INPP4A,INPP5D,PLCZ1,CALM3,MTMR3 |
| Focal adhesion | SEPP1,COL2A1,PARVG,LAMA3,RAC3B,TNW,MAPK6,THBS2,RAP1A,MYL2 |
| Regulation of Actin Cytoskeleton | PIK3R1,ROCK2A,MRAS,GNA13A,WAS,NRAS,CHRM2A,MAPK1,FGF13,PXN |
| Phospholipase D signaling pathway | SYK,AKT2,PIK3CD,CXCR2,CYTH4,RRAS,SHC3,FYN,PIK3R2,AGTR1B |
| Metabolic pathways | CTPS2,GOT1,XDH,TKTL2,NDUFV1,ATP6V1B1,ITPA,B3GNT1,PIGQ,NDUFS8A |
Protein Function
PIP5K1C has several biochemical functions, for example, 1-phosphatidylinositol-4-phosphate 5-kinase activity,ATP binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PIP5K1C itself. We selected most functions PIP5K1C had, and list some proteins which have the same functions with PIP5K1C. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| 1-phosphatidylinositol-4-phosphate 5-kinase activity | PIP5K1B,PIP4K2C,PIKFYVE,PIP4K2B,PIP5K1A,PIP4K2A,PIP5KL1 |
| ATP binding | GUCY2F,DNAJA3A,JAK2A,EIF2AK3,HSPA6,NMRK2,CMPK,MAPK15,APAF1,CDC7 |
| protein binding | EDNRA,ERCC8,TRMT61B,CRLF3,TNS3,CDCP1,TBP,RWDD1,MYL2,TMED9 |
Interacting Protein
PIP5K1C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PIP5K1C here. Most of them are supplied by our site. Hope this information will be useful for your research of PIP5K1C.
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