OTUD7B
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Official Full Name
OTU domain containing 7B -
Overview
OTU domain-containing protein 7B is a protein that in humans is encoded by the OTUD7B gene. -
Synonyms
OTUD7B;OTU domain containing 7B;ZA20D1, zinc finger, A20 domain containing 1;OTU domain-containing protein 7B;CEZANNE;zinc finger protein Cezanne;zinc finger, A20 domain containing 1;cellular zinc finger anti-NF-kappaB Cezanne;zinc finger A20 dom
Recombinant Proteins
- Human
- Mouse
- Rhesus macaque
- Zebrafish
- E.coli
- Mammalian Cells
- Wheat Germ
- HEK293
- Insect Cells
- His
- GST
- Non
- Strep
- Avi
- Fc
- DDK
- Myc
Involved Pathway
OTUD7B involved in several pathways and played different roles in them. We selected most pathways OTUD7B participated on our site, such as Death Receptor Signalling,Regulation of TNFR1 signaling,Signal Transduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with OTUD7B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Death Receptor Signalling | RBCK1,OTULIN,USP2,FAM105B,TAX1BP1,SHRPRBCK1R,CYLD,OTULINB,GNB2L1,USP4 |
| TNFR1-induced proapoptotic signaling | USP2,USP4 |
| Signal Transduction | RARGA,RTKN,CRHB,RGS6,PCSK6,CCNT2A,UTS2,USP34,RPGRIP1L,NOXA1 |
| TNFR1-induced NFkappaB signaling pathway | USP2,SHARPIN,SHRPRBCK1R,USP4,RNF31 |
| Regulation of TNFR1 signaling | SHRPRBCK1R,USP4,RBCK1,TAX1BP1B,RNF31,SHARPIN,USP2,TAX1BP1,FAM105B,OTULIN |
| TNF signaling | OTULIN,RNF31,SHRPRBCK1R,USP2,SHARPIN,USP4,TAX1BP1,TAX1BP1B,OTULINB,FAM105B |
Protein Function
OTUD7B has several biochemical functions, for example, DNA binding,K63-linked polyubiquitin binding,Lys48-specific deubiquitinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by OTUD7B itself. We selected most functions OTUD7B had, and list some proteins which have the same functions with OTUD7B. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| DNA binding | FOSB,SCRT1,ATF4B1,EP300,HOXB6B,ZNF292A,FOXC1,CR2,FAM60AL,ZC3H3 |
| zinc ion binding | RNF130,MSRB1,VPS11,MT1A,MEP1A.1,SUV39H2,PPARDB,ZFP326,ZSWIM3,ZZZ3 |
| Lys48-specific deubiquitinase activity | YOD1,ATXN3 |
| K63-linked polyubiquitin binding | PRPF8,SPRTN,RNF168,TAB2,RNF169,SQSTM1,UIMC1,ZRANB1B,ATRIP,IKBKG |
| cysteine-type peptidase activity | CTSSB.1,CTSK,SENP3B,OTUD4,OTUD5A,USP12A,CTSL2,USP27X,ATG4B,CTSLL |
| ubiquitin-specific protease activity | USP22,OTUB2,USP33,OTUD6A,USP44,OTUD5,USP19,USP38,USP31,USP10 |
| protein binding | KHDC3,PPP1R12B,SLC25A23,KIAA1267,RAB11B,KIRREL3,CDCA4,ARHGEF10,ZNF217,POLR3GL |
Interacting Protein
OTUD7B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with OTUD7B here. Most of them are supplied by our site. Hope this information will be useful for your research of OTUD7B.
CCDC50;PIK3R3;PARK7;NUP155;CASP8;SLC9A3R2;ACAD9;HIF1AN;TRAF6;YWHAB;ZDHHC17;TNIP2
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