NKX6-2
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Official Full Name
NK6 homeobox 2 -
Synonyms
NKX6-2;NK6 homeobox 2;NK6 transcription factor related, locus 2 (Drosophila);homeobox protein Nkx-6.2;GTX;NKX6.1;NKX6B;NKX6.2;Homeobox protein NK-6 homolog B;Homeobox protein Nkx 6.2;MGC126684;NK6 transcription factor related, locus 2;NKX62_HUMAN;homeobox 6B;OTTHUMP00000020781;NK homeobox family 6, B;glial and testis-specific homeobox protein
Recombinant Proteins
- Human
- Rhesus macaque
- Chicken
- Mouse
- E.coli
- Mammalian Cells
- HEK293
- Wheat Germ
- His
- DDK
- Myc
- Avi
- Fc
- GST
Involved Pathway
NKX6-2 involved in several pathways and played different roles in them. We selected most pathways NKX6-2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with NKX6-2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
NKX6-2 has several biochemical functions, for example, RNA polymerase II core promoter proximal region sequence-specific DNA binding,transcription factor activity, sequence-specific DNA binding,transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NKX6-2 itself. We selected most functions NKX6-2 had, and list some proteins which have the same functions with NKX6-2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding | HELT,ZGPAT,NKX6-1,CC2D1B,SP3,MZF1,NR2E1,NFATC2,DLX4,FOXO1 |
| transcription factor activity, sequence-specific DNA binding | ZNF19,ZNF215,POU5F2,LHX1,SMAD3,MLLT10,GTF3A,ZNF461,ZNF691,SALL1A |
| RNA polymerase II core promoter proximal region sequence-specific DNA binding | MSX2,CC2D1B,ATF7,ZIC3,GATA1,NFIB,FEZF2,PBX1,TCF3A,JUNB |
Interacting Protein
NKX6-2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NKX6-2 here. Most of them are supplied by our site. Hope this information will be useful for your research of NKX6-2.
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