NFE2
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Official Full Name
nuclear factor (erythroid-derived 2), 45kDa -
Overview
Transcription factor NF-E2 45 kDa subunit is a protein that in humans is encoded by the NFE2 gene. -
Synonyms
NFE2;nuclear factor (erythroid-derived 2), 45kDa;nuclear factor (erythroid derived 2), 45kD;transcription factor NF-E2 45 kDa subunit;NF E2;erythroid-derived 2 45 kDa subunit;Leucine zipper protein NF-E2;Leucine zipper protein NFE2;NFE2_HUMAN;Nuclear factor (erythroid derived 2), 45kDa;Nuclear factor;Nuclear factor, erythroid derived 2 45 kDa subunit;p45;p45 NF-E2;p45 NFE2;Transcription factor NFE2 45 kDa subunit;OTTHUMP00000242012;OTTHUMP00000242013;OTTHUMP00000242015;nuclear factor, erythroid-derived 2 45 kDa subunit;NF-E2
Recombinant Proteins
- Human
- Mouse
- Rhesus macaque
- Rat
- Zebrafish
- E.coli
- Mammalian Cells
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- GST
- HIS
- His
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
NFE2 involved in several pathways and played different roles in them. We selected most pathways NFE2 participated on our site, such as Factors involved in megakaryocyte development and platelet production,Hemostasis, which may be useful for your reference. Also, other proteins which involved in the same pathway with NFE2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Hemostasis | NADL1.1,SERPINB8,GLG1B,GATA1,HRG,CFHL2,ABHD12,BRPF3,CFHL4,F9A |
| Factors involved in megakaryocyte development and platelet production | DOCK9,GATA5,KIF5B,EHD1,HBBE1.1,GATA1,RACGAP1,KIF2C,KIF15,KLC3 |
Protein Function
NFE2 has several biochemical functions, for example, WW domain binding,protein N-terminus binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NFE2 itself. We selected most functions NFE2 had, and list some proteins which have the same functions with NFE2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | PRAME,GTF2A1,CCKBR,UCHL3,IFNA4,ZFPM2,ZWINT,TIMM8A,BAG2,EIF4A1 |
| transcription regulatory region sequence-specific DNA binding | DDIT3,NFE2L1A,CREB3L3,NFE2L3,MKL1,NR5A1,NKX3-1,ARNTL,KCNA3,ATF3 |
| sequence-specific DNA binding | HOXA5A,TCF7L2,ZNF205,IRX1A,FOXG1B,ZNF232,HOXB1,NKX1.2LA,IRX4,ESRRA |
| transcription coactivator activity | MMS19,CITED1,UTF1,NCOA3,ABT1,MED16,JUP,PRDM16,HINFP,SMARCB1 |
| WW domain binding | TNK2,PMEPA1,TMEM128,TCEAL6,WBP11,TCEAL8,WBP5,TCEAL5,DAZAP2,TCEAL3 |
| transcription factor activity, sequence-specific DNA binding | HNF1BB,HOXA13,FOXO6,ETV6,KDM5A,LEF1,ETV5A,DLX2,HOXD3,MKL1 |
| protein N-terminus binding | EXOC4,EXOC5,NBN,THAP7,PDCD10,RPS21,TDRD7,ERCC5,RND2,MAU2 |
Interacting Protein
NFE2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NFE2 here. Most of them are supplied by our site. Hope this information will be useful for your research of NFE2.
BTRC;MAFG;ATF7;Dlg4;NFE2L1;meq_gahvm;CREBZF;NFE2L3;TXN;q7cfv4_yerpe;PHYHIP;q9wmx2-pro_0000037551
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