NAT6
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Official Full Name
N-acetyltransferase 6 (GCN5-related) -
Overview
This gene encodes a member of the N-acetyltransferase family. N-acetyltransferases modify proteins by transferring acetyl groups from acetyl CoA to the N-termini of protein substrates. The encoded protein is a cytoplasmic N-acetyltransferase with a substrate specificity for proteins with an N-terminal methionine. This gene is located in the tumor suppressor gene region on chromosome 3p21.3 and the encoded protein may play a role in cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed. This gene overlaps and is on the same strand as hyaluronoglucosaminidase 3, and some transcripts of each gene share a portion of the first exon. -
Synonyms
NAT6;N-acetyltransferase 6 (GCN5-related);N acetyltransferase 6;N-acetyltransferase 6;FUS2;OTTMUSP00000046404;OTTMUSP00000046405;OTTMUSP00000046406;AI225910;FUS 2;OTTMUSP00000046403;Protein fus 2;Protein fusion 2;protein fusion-2;OTTHUMP00000211057;OTTHUMP00000211058;OTTHUMP00000211060;OTTHUMP00000211061;OTTHUMP00000211062;OTTHUMP00000211063;FUS-2
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| NAT6-132H | Recombinant Human N-acetyltransferase 6, His-tagged | E.coli | Human | His |
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| NAT6-163H | Recombinant Human NAT6 protein, T7-tagged | E.coli | Human | T7 | 308 a.a. |
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| NAT6-27229TH | Recombinant Human NAT6, His-tagged | E.coli | Human | His | Full L. 1-308 a.a. |
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| NAT6-827H | Recombinant Human NAT6, T7-tagged | E.coli | Human | T7 | 1-286 a.a. |
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| NAT6-3963HCL | Recombinant Human NAT6 293 Cell Lysate | HEK293 | Human | Non |
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Involved Pathway
NAT6 involved in several pathways and played different roles in them. We selected most pathways NAT6 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with NAT6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
NAT6 has several biochemical functions, for example, N-acetyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NAT6 itself. We selected most functions NAT6 had, and list some proteins which have the same functions with NAT6. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| N-acetyltransferase activity | CML2,AANAT,NAT15,SAT1A.1,SAT1A.2,MBOAT7,MBOAT4,NAT9,LPCAT3,SAT2A |
Interacting Protein
NAT6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NAT6 here. Most of them are supplied by our site. Hope this information will be useful for your research of NAT6.
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References
- Srivastava, P; Khandokar, YB; et al. Structural Characterization of a Gcn5-Related N-Acetyltransferase from Staphylococcus aureus. PLOS ONE 9:-(2014).
- Smith, CA; Toth, M; et al. Structure of the bifunctional aminoglycoside-resistance enzyme AAC(6 ')-Ie-APH(2 '')-Ia revealed by crystallographic and small-angle X-ray scattering analysis. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY 70:2754-2764(2014).
