MYLK3
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Official Full Name
myosin light chain kinase 3 -
Synonyms
MYLK3;myosin light chain kinase 3;putative myosin light chain kinase 3;caMLCK;MLC kinase;MLCK;cardiac-MyBP-C associated Ca/CaM kinase;cardiac-MyBP-C-associated Ca/CaM kinase;MLCK2;MGC126319;MGC126320
Recombinant Proteins
- Mouse
- Human
- Rat
- Zebrafish
- Mammalian Cells
- Sf9 Cells
- E.coli
- HEK293
- Wheat Germ
- His
- GST
- T7
- Non
- Avi
- Fc
Involved Pathway
MYLK3 involved in several pathways and played different roles in them. We selected most pathways MYLK3 participated on our site, such as Calcium signaling pathway,cGMP-PKG signaling pathway,Vascular smooth muscle contraction, which may be useful for your reference. Also, other proteins which involved in the same pathway with MYLK3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Platelet activation | ITPR3,BTK,ARHGEF1,ROCK1,GNAS,PIK3CG,PIK3CD,ROCK2,MAPK1,GP5 |
| cGMP-PKG signaling pathway | ATP2A3,NPPB,FXYD2,TRPC6,VDAC2,GNAI2,PDE5A,PPP1CC,ATF4,PLCB4 |
| Gastric acid secretion | MYLK2,CAMK2A,KCNJ15,ATP4A,Car2,PLCB2,KCNJ10,ATP1B3,Slc4a2,ATP1A4 |
| Vascular smooth muscle contraction | ADORA2AB,KCNMB3,KCNMA1A,MAP2K2,AGTR1A,PRKCA,PTGIR,GUCY1A3,CALM1,PPP1R12B |
| Focal adhesion | MAPK6,PPP1R12A,ITGB3,VCLA,PPP1R12C,COL4A1,RAP1B,DIAPH1,MYL12B,Reln |
| Regulation of Actin Cytoskeleton | PIKFYVE,ACTB1,RAF1B,ITGB2L,CDC42L,GSN,BDKRB2,SOS1,PIP5KL1,ITGA2B |
| Calcium signaling pathway | CD38,PPP3R1,CALM3A,CACNA1SA,SLC8A2B,PTK2BB,PHKB,SLC25A31,GRPR,ERBB3 |
| Oxytocin signaling pathway | MAP2K1,PIK3CD,ROCK1,PRKCG,PRKAB1,ACTG1,CACNB3,SRC,PIK3CA,CACNG6 |
Protein Function
MYLK3 has several biochemical functions, for example, ATP binding,calmodulin-dependent protein kinase activity,myosin light chain kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MYLK3 itself. We selected most functions MYLK3 had, and list some proteins which have the same functions with MYLK3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| myosin light chain kinase activity | MYLK2,MYLK |
| calmodulin-dependent protein kinase activity | NETO2,DCX,CAMK1D,CAMK2D,MAPKAPK2A,CAMK4,MAPKAPK2,CAMK1,PTK2B,CAMK2D2 |
| ATP binding | ABCG4B,FGFR1A,DDX6,CLCN6,MAPK11,SLC22A5,SKIV2L2,ACSS2,GSK3AB,PSMC3 |
Interacting Protein
MYLK3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MYLK3 here. Most of them are supplied by our site. Hope this information will be useful for your research of MYLK3.
HSP90AB1;ALB
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References
- Wang, HG; Dong, JN; et al. Anti-mouse CD52 monoclonal antibody ameliorates intestinal epithelial barrier function in interleukin-10 knockout mice with spontaneous chronic colitis. IMMUNOLOGY 144:254-262(2015).
- Ayoglu, B; Chaouch, A; et al. Affinity proteomics within rare diseases: a BIO-NMD study for blood biomarkers of muscular dystrophies. EMBO MOLECULAR MEDICINE 6:918-936(2014).
