MYL4
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Official Full Name
myosin, light chain 4, alkali; atrial, embryonic -
Overview
Myosin is a hexameric ATPase cellular motor protein. It is composed of two myosin heavy chains, two nonphosphorylatable myosin alkali light chains, and two phosphorylatable myosin regulatory light chains. This gene encodes a myosin alkali light chain that is found in embryonic muscle and adult atria. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. -
Synonyms
MYL4;myosin, light chain 4, alkali;atrial, embryonic;myosin, light polypeptide 4, alkali;myosin light chain 4;ALC1;AMLC;GT1;myosin;atrial/fetal muscle;light chain;PRO1957;embryonic muscle/atrial isoform;ALC 1;Atrial/embryonic alkali myosin light chain;GT 1;MLC 1;MLC1;MYL 4;MYL4_HUMAN;Myosin atrial/fetal muscle light chain;Myosin light chain 1;Myosin light chain 1 embryonic muscle/atrial isoform;Myosin light chain 4 alkali atrial embryonic;Myosin light chain alkali GT 1 isoform;Myosin light chain alkali GT-1 isoform;Myosin light polypeptide 4 alkali atrial embryonic;Myosin light polypeptide 4;myosin, atrial/fetal muscle, light chain;myosin light chain 1, embryonic muscle/atrial isoform
Recombinant Proteins
- Human
- Zebrafish
- Chicken
- Mouse
- Wheat Germ
- E.coli
- Mammalian Cells
- Human
- HEK293
- In Vitro Cell Free System
- Non
- His
- Myc&DDK
- GST
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| MYL4-29362TH | Recombinant Human MYL4 | Wheat Germ | Human | Non | 197 amino acids |
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| MYL4-30265TH | Recombinant Human MYL4, His-tagged | E.coli | Human | His | 197 amino acids |
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| MYL4-3085Z | Recombinant Zebrafish MYL4 | Mammalian Cells | Zebrafish | His |
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| MYL4-4751H | Recombinant Human MYL4, His-tagged | Human | Human | His |
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| MYL4-6857H | Recombinant Human Myosin, Light Chain 4, Alkali; Atrial, Embryonic, His-tagged | E.coli | Human | His | 1-197aa |
|
| MYL4-7028C | Recombinant Chicken MYL4 | Mammalian Cells | Chicken | His |
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| Myl4-8029M | Recombinant Mouse Myl4 protein, His-tagged | E.coli | Mouse | His | Lys4~Val187 |
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| MYL4-4026HCL | Recombinant Human MYL4 293 Cell Lysate | HEK293 | Human | Non |
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| MYL4-1355H | Recombinant Human MYL4 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293 | Human | Myc&DDK |
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| MYL4-1565H | Recombinant Human MYL4 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293 | Human | Myc&DDK |
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| MYL4-323HF | Recombinant Full Length Human MYL4 Protein | In Vitro Cell Free System | Human | Full L. 197 amino acids |
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| Myl4-4252M | Recombinant Mouse Myl4 Protein, Myc/DDK-tagged | HEK293 | Mouse | Myc&DDK |
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| MYL4-5811H | Recombinant Human MYL4 Protein, GST-tagged | Wheat Germ | Human | GST |
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| MYL4-6761HF | Recombinant Full Length Human MYL4 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 197 amino acids |
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Involved Pathway
MYL4 involved in several pathways and played different roles in them. We selected most pathways MYL4 participated on our site, such as Cardiac muscle contraction,Adrenergic signaling in cardiomyocytes, which may be useful for your reference. Also, other proteins which involved in the same pathway with MYL4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cardiac muscle contraction | ATP1B1,UQCRFS1,ATP1A1B,ATP1A1A.1,ATP1B3B,MYL2,ATP1B1A,TNNT2,COX5B2,TPM4 |
| Adrenergic signaling in cardiomyocytes | PRKCA,CREB1A,CAMK2G1,MYH7,PIK3CD,PIK3R5,PPP1CBL,ATP1A1,ADCY1,PPP2R5CB |
Protein Function
MYL4 has several biochemical functions, for example, actin filament binding,actin monomer binding,calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MYL4 itself. We selected most functions MYL4 had, and list some proteins which have the same functions with MYL4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| actin monomer binding | MKL1,COBLL1,MYL3,LMOD3,TWF1,MYL2,PFN2,TMSB4Y,PFN1,ABL1 |
| myosin II heavy chain binding | MYL3 |
| actin filament binding | FLNC,CORO1A,WIPF3,PLDN,SCIN,MTSS1,WIPF1,CTNNA1,WIPF1A,SVIL |
| calcium ion binding | PCDH1G31,FSTL1B,DNASE1L3,GUCA1D,CETN3,ITSN2B,SPOCK2,PADI3,NDUFAB1,FSTL5 |
Interacting Protein
MYL4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MYL4 here. Most of them are supplied by our site. Hope this information will be useful for your research of MYL4.
VCAM1;PYROXD2;FN1;ALB
Resources
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References
- Cheng, W; Yu, Z; et al. Perfluorooctane sulfonate (PFOS) induced embryotoxicity and disruption of cardiogenesis. TOXICOLOGY IN VITRO 27:1503-1512(2013).
- Lisowski, P; Juszczak, GR; et al. Stress susceptibility-specific phenotype associated with different hippocampal transcriptomic responses to chronic tricyclic antidepressant treatment in mice. BMC NEUROSCIENCE 14:-(2013).
