MT-ND4
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Official Full Name
mitochondrially encoded NADH dehydrogenase 4 -
Overview
NADH dehydrogenase subunit 4, also known as ND4, is a mitochondrial gene present in many species of organisms, including humans. -
Synonyms
MT-ND4;mitochondrially encoded NADH dehydrogenase 4;MTND4, NADH dehydrogenase 4;NADH dehydrogenase, subunit 4 (complex I);complex I ND4 subunit;NAD4;NADH ubiquinone oxidoreductase chain 4;ND4;MTND4;NADH dehydrogenase subunit 4;NADH-ubiquinone oxidoreductase chain 4;NADH4;NU4M_HUMAN
Recombinant Proteins
- Human
- Caiman crocodilus (Spectacled caiman) (Caiman sclerops)
- Bothrops erythromelas (Caatinga lance head)
- Crotalus lepidus (Banded rock rattlesnake)
- Protobothrops flavoviridis (Habu) (Trimeresurus flavoviridis)
- Gloydius intermedius (Central Asian pit viper) (Agkistrodon intermedius)
- Microtus pennsylvanicus (Meadow vole)
- Tarsius syrichta (Philippine tarsier)
- Agkistrodon piscivorus piscivorus
- Azemiops feae (Fea's viper)
- Crotalus Adamanteus
- Phodopus sungorus (Striped hairy-footed hamster) (Djungarian hamster)
- Atropoides nummifer (Jumping pit viper) (Porthidium nummifer)
- Protobothrops elegans (Elegant pitviper) (Trimeresurus elegans)
- Trimeresurus albolabris (White-lipped pit viper) (Cryptelytrops albolabris)
- Porthidium ophryomegas (Slender hognose viper)
- Sistrurus miliarius (Pigmy rattlesnake) (Crotalus miliarius)
- Crotalus oreganus concolor (Midget faded rattlesnake) (Crotalus viridis concolor)
- Porthidium nasutum (Hognosed pitviper) (Bothrops nasutus)
- Calloselasma rhodostoma (Malayan pit viper) (Agkistrodon rhodostoma)
- Ovophis okinavensis (Ryukyu Island pit viper) (Trimeresurus okinavensis)
- Bothrops bilineatus (Green jararaca) (Bothriopsis bilineata)
- Bothrocophias hyoprora (Amazonian hognose viper) (Porthidium hyoprora)
- Deinagkistrodon acutus (Hundred-pace snake) (Agkistrodon acutus)
- Trimeresurus cantori (Cantor's pit viper) (Cryptelytrops cantori)
- Gloydius blomhoffii (Mamushi) (Agkistrodon halys blomhoffi)
- Causus rhombeatus (Rhombic night adder)
- Trimeresurus stejnegeri (Chinese green tree viper) (Viridovipera stejnegeri)
- Atropoides picadoi (Picado's pit viper) (Porthidium picadoi)
- Macaca fascicularis
- Bothriechis schlegelii (Eyelash palm pitviper)
- Tropidolaemus wagleri (Wagler's pit viper) (Trimeresurus wagleri)
- Bothrops asper (Terciopelo)
- Cerrophidion godmani (Porthidium godmani) (Bothrops godmani)
- Bothriechis lateralis (Side-striped palm pitviper)
- Hypnale hypnale (Merrem's hump-nosed viper)
- Lachesis muta muta (Bushmaster)
- Agkistrodon contortrix
- Wheat Germ
- E.coli
- Non
- His
Involved Pathway
MT-ND4 involved in several pathways and played different roles in them. We selected most pathways MT-ND4 participated on our site, such as Oxidative phosphorylation,Metabolic pathways,Parkinsons disease, which may be useful for your reference. Also, other proteins which involved in the same pathway with MT-ND4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolic pathways | ITPK1A,AKR1B1,DHRS3,FUT9,HOGA1,NOS2,ACSL5,HSD3B7,ADH6,PFKP |
| Oxidative phosphorylation | ATP6V0A2B,ATP5D,NDUFA7,COX7B,COX5A,NDUFA5,COX7A2L,NDUFS8,PPA1,UQCRC2A |
| Parkinsons disease | MT-ND1,NDUFA11,GNAI2,GNAI1,VDAC3,COX7B2,NDUFB6,SDHC,COX6B2,UQCR11 |
Protein Function
MT-ND4 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by MT-ND4 itself. We selected most functions MT-ND4 had, and list some proteins which have the same functions with MT-ND4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
MT-ND4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MT-ND4 here. Most of them are supplied by our site. Hope this information will be useful for your research of MT-ND4.
NDUFA2;SP1;ZNF16;CTCF;GRB2;ATM;q9wmx2-pro_0000037550;NDUFS4;NDUFS5;NDUFS6;NDUFA6;NDUFA11;ECSIT;TIMMDC1
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References
- Mottaghi-Dastjerdi, N; Soltany-Rezaee-Rad, M; et al. Identification of novel genes involved in gastric carcinogenesis by suppression subtractive hybridization. HUMAN & EXPERIMENTAL TOXICOLOGY 34:3-11(2015).
- Morgan, MA; Markus, B; et al. NADH dehydrogenase subunit 4 variant sequences in childhood acute myeloid leukaemia. BRITISH JOURNAL OF HAEMATOLOGY 161:891-895(2013).
