MSRB3
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Official Full Name
methionine sulfoxide reductase B3 -
Overview
The protein encoded by this gene catalyzes the reduction of methionine sulfoxide to methionine. This enzyme acts as a monomer and requires zinc as a cofactor. Several transcript variants encoding two different isoforms have been found for this gene. One of the isoforms localizes to mitochondria while the other localizes to endoplasmic reticula. -
Synonyms
MSRB3;methionine sulfoxide reductase B3;deafness, autosomal recessive 74 , DFNB74;methionine-R-sulfoxide reductase B3;DKFZp686C1178;FLJ36866;Methionine R sulfoxide reductase B mitochondrial;MSRB3_HUMAN;methionine-R-sulfoxide reductase B3, mitochondrial;DFNB74
Recombinant Proteins
- Human
- Rhesus macaque
- Zebrafish
- Chicken
- Mouse
- E.coli
- Mammalian Cells
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- His
- Fc
- Non
- His&Fc&Avi
- GST
- Myc&DDK
Involved Pathway
MSRB3 involved in several pathways and played different roles in them. We selected most pathways MSRB3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MSRB3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
MSRB3 has several biochemical functions, for example, peptide-methionine (R)-S-oxide reductase activity,protein binding,zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MSRB3 itself. We selected most functions MSRB3 had, and list some proteins which have the same functions with MSRB3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| peptide-methionine (R)-S-oxide reductase activity | MSRB1A,MSRB1,TXN2,MSRB2,MSRB1B |
| protein binding | CARD8,DCBLD2,RAET1D,GPN3,AMHR2,NCF4,ZFP932,AJUBA,SELL,CYBA |
| zinc ion binding | PRICKLE1A,FTR14,PEX10,SRSF7B,USP13,PGLYRP6,SHANK3,ZDHHC17,HIF1AN,RNFT1 |
Interacting Protein
MSRB3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MSRB3 here. Most of them are supplied by our site. Hope this information will be useful for your research of MSRB3.
TCF4;GOLGA2;TRIP6;PRDM4;LNX2
Resources
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References
- Taungjaruwinai, WM; Bhawan, J; et al. Differential Expression of the Antioxidant Repair Enzyme Methionine Sulfoxide Reductase (MSRA and MSRB) in Human Skin. AMERICAN JOURNAL OF DERMATOPATHOLOGY 31:427-431(2009).
