MOS
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Official Full Name
v-mos Moloney murine sarcoma viral oncogene homolog -
Overview
MOS is a serine/threonine kinase that activates the MAP kinase cascade through direct phosphorylation of the MAP kinase;activator MEK (MAP2K1; MIM 176872) (Prasad et al., 2008 (PubMed 18246541)). -
Synonyms
MOS;v-mos Moloney murine sarcoma viral oncogene homolog;proto-oncogene serine/threonine-protein kinase mos;c-mos;proto-oncogene c-Mos;oocyte maturation factor mos;oncogene MOS, Moloney murine sarcoma virus;MSV;MGC119962;MGC119963
Recombinant Proteins
- Zebrafish
- Chicken
- Human
- Mammalian Cells
- HEK293
- Insect Cells
- Wheat Germ
- Sf21 Cells
- In Vitro Cell Free System
- His
- Non
- GST
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| MOS-11620Z | Recombinant Zebrafish MOS | Mammalian Cells | Zebrafish | His |
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| MOS-3161C | Recombinant Chicken MOS | Mammalian Cells | Chicken | His |
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| MOS-4247HCL | Recombinant Human MOS 293 Cell Lysate | HEK293 | Human | Non |
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| MOS-5484H | Active Recombinant Human MOS Protein, GST-tagged | Insect Cells | Human | GST |
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| MOS-5485H | Recombinant Human MOS Protein, GST-tagged | Wheat Germ | Human | GST |
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| MOS-6055HF | Active Recombinant Full Length Human MOS Protein, GST-tagged | Sf21 Cells | Human | GST | Full L. 1-346 |
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| MOS-6314HF | Recombinant Full Length Human MOS Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 346 amino acids |
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Involved Pathway
MOS involved in several pathways and played different roles in them. We selected most pathways MOS participated on our site, such as MAPK signaling pathway,Oocyte meiosis,Regulation of actin cytoskeleton, which may be useful for your reference. Also, other proteins which involved in the same pathway with MOS were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Oocyte meiosis | SPDYB,YWHAG1,SLK,CUL1B,SMC1A,CAMK2D,PPP1CB,PRKACB,CDK1,CALML3 |
| Regulation of Actin Cytoskeleton | ACTN2B,FGF14,ARHGEF7B,MSNA,PPP1CB,VAV2,PAK2B,PDGFC,ITGA2B,MYL2B |
| Progesterone-mediated oocyte maturation | BRAF,GNAI2B,CDC26,PIK3CD,PDE3B,CCNB3,GNAIA,RPS6KA3B,ANAPC13,INS |
| MAPK signaling pathway | CACNB4,TRAF6,PAK1,CACNG6A,JIP1,HSPB1,MAP3K7,RELB,CDC42L2,GRB2B |
Protein Function
MOS has several biochemical functions, for example, ATP binding,MAP kinase kinase kinase activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MOS itself. We selected most functions MOS had, and list some proteins which have the same functions with MOS. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | CDKL4,PFKFB2A,UBE2D1B,ATP1A1A.4,KDRL,TRP53,DDX39AA,KALRN,TWF1,PKM2 |
| MAP kinase kinase kinase activity | MAP3K3,MAP3K6,RAF1,MAP3K4,BRAF,YSK4,ALPK2,MAP3K5,MAP3K12,MAP3K13 |
| protein serine/threonine kinase activity | PIM3,PBK,STK32A,OXSR1B,MAPKAPK5,VRK1,CDK12,NEK11,CDC42BPB,RIPK2 |
| protein binding | AIDA,DNA2,POT1,TCERG1,IKZF2,GATA5,CDKN2AIP,EEF1A2,MIS12,ADORA2A |
Interacting Protein
MOS has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MOS here. Most of them are supplied by our site. Hope this information will be useful for your research of MOS.
KRT13;CCDC102B;HOMER3;80125;CCNDBP1;GFAP;TRIM27
Resources
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References
- Shan, LF; Li, M; et al. PCR-Based Assays versus Direct Sequencing for Evaluating the Effect of KRAS Status on Anti-EGFR Treatment Response in Colorectal Cancer Patients: A Systematic Review and Meta-Analysis. PLOS ONE 9:-(2014).
- Liu, X; Byrd, JA; et al. Arginine and vitamin E improve the immune response after a Salmonella challenge in broiler chicks. POULTRY SCIENCE 93:882-890(2014).
