MCOLN2
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Official Full Name
mucolipin 2 -
Overview
Mucolipins constitute a family of cation channel proteins with homology to the transient receptor potential;superfamily. In mammals, the mucolipin family includes 3 members, MCOLN1 (MIM 605248), MCOLN2, and MCOLN3 (MIM;607400), that exhibit a common 6-membrane-spanning topology. Homologs of mammalian mucolipins exist in Drosophila and;C. elegans. Mutations in the human MCOLN1 gene cause mucolipodosis IV (MIM 262650) (Karacsonyi et al., 2007 (PubMed;17662026)). -
Synonyms
MCOLN2;mucolipin 2;mucolipin-2;FLJ36691;TRP ML2;TRPML2;TRP-ML2
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| MCOLN2-11367Z | Recombinant Zebrafish MCOLN2 | Mammalian Cells | Zebrafish | His |
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| MCOLN2-9645M | Recombinant Mouse MCOLN2 Protein | Mammalian Cells | Mouse | His |
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| MCOLN2-5419M | Recombinant Mouse MCOLN2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| MCOLN2-5419M-B | Recombinant Mouse MCOLN2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| RFL12255MF | Recombinant Full Length Mouse Mucolipin-2(Mcoln2) Protein, His-Tagged | E.coli | Mus musculus | His | Full L. Full Length (1-566) |
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| RFL25089HF | Recombinant Full Length Human Mucolipin-2(Mcoln2) Protein, His-Tagged | E.coli | Human | His | Full L. Full Length (1-566) |
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Involved Pathway
MCOLN2 involved in several pathways and played different roles in them. We selected most pathways MCOLN2 participated on our site, such as Ion channel transport,Stimuli-sensing channels,TRP channels, which may be useful for your reference. Also, other proteins which involved in the same pathway with MCOLN2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Transmembrane transport of small molecules | SLC43A2B,SLC30A6,SLC17A7A,SLC12A1,SLC15A1B,SLC30A2,SLC28A2,SLC39A14,ATP11C,BSND |
| Ion channel transport | SRI,NHEDC1,TRPC4AP,ATP11C,CLCN1A,ATP6V1G3,GABRR2A,CLCN4-2,FXYD3,TRPM1 |
| Stimuli-sensing channels | UNC79,SLC9A10,TTYH3B,ANO5B,TRPM6,TRPM1A,TRPM4A,OSTM1,ANO9,CLCN6 |
| TRP channels | TRPC4APA,TRPC4AP,TRPM1A,TRPC5A,TRPM4A,TRPC5,TRPM6,TRPM4C,TRPV3,TRPA1B |
Protein Function
MCOLN2 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by MCOLN2 itself. We selected most functions MCOLN2 had, and list some proteins which have the same functions with MCOLN2. You can find most of the proteins on our site.
| Function | Related Protein |
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Interacting Protein
MCOLN2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MCOLN2 here. Most of them are supplied by our site. Hope this information will be useful for your research of MCOLN2.
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