MCM7
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Official Full Name
minichromosome maintenance complex component 7 -
Overview
The minichromosome maintenance (MCM) 2-7 proteins are a family of six related proteins required for the initiation and elongation of DNA replication. MCM2-7 bind together to form the heterohexameric MCM complex that is thought to act as a replicative heli -
Synonyms
MCM7;minichromosome maintenance complex component 7;MCM2, MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) , minichromosome maintenance deficient (S. cerevisiae) 7;DNA replication licensing factor MCM7;CDC47;CDC47 homolog;homolog of S.
Recombinant Proteins
- Zebrafish
- Human
- Mouse
- Mammalian Cells
- Wheat Germ
- E.coli
- HEK293
- In Vitro Cell Free System
- His
- Non
- Myc&DDK
- His&Fc&Avi
- GST
- Flag
Involved Pathway
MCM7 involved in several pathways and played different roles in them. We selected most pathways MCM7 participated on our site, such as DNA replication,Cell cycle, which may be useful for your reference. Also, other proteins which involved in the same pathway with MCM7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cell cycle | MCM6L,RBBP8,NEK9,RNF168,CLIP1,NPM1,GADD45BA,HDAC6,SMC3,MND1 |
| DNA Replication | POLD4,DBF4,RFC1,GMNN,rnhA,RPA4,CDT1,MCM10,PRIM1,RFC5 |
Protein Function
MCM7 has several biochemical functions, for example, ATP binding,contributes_to ATP-dependent DNA helicase activity,contributes_to DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MCM7 itself. We selected most functions MCM7 had, and list some proteins which have the same functions with MCM7. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | TTC9C,CD151,DOK3,ISCA2,TBX6,MRPL28,GRIN3A,TMPRSS2,PGAP2,SCAND1 |
| contributes_to DNA binding | ARNTL1B,MAFGA,GTF3C3,MRE11A,MLXIPL,TCF3,SMAD4,NFE2L2A,CLOCKA,FOXH1 |
| ATP binding | CAMK1GB,UPF1,DHX32,MARK4,CDK9,ATP13A3,SPG7,ACVR1,PDPK1A,ERBB4 |
| contributes_to ATP-dependent DNA helicase activity | MRE11A,MCM4,RAD50,MCM6,NBN |
| single-stranded DNA binding | NABP1,NABP2,SSBP1,YBX1,RPA4,ANXA1,CTC1,TSNAX,RAD23A,TSN |
Interacting Protein
MCM7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MCM7 here. Most of them are supplied by our site. Hope this information will be useful for your research of MCM7.
MCM4;MCMBP
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References
- Borgogna, C; Lanfredini, S; et al. Improved detection reveals active beta-papillomavirus infection in skin lesions from kidney transplant recipients. MODERN PATHOLOGY 27:1101-1115(2014).
- Ishibashi, Y; Kinugasa, T; et al. Minichromosome Maintenance Protein 7 Is a Risk Factor for Recurrence in Patients with Dukes C Colorectal Cancer. ANTICANCER RESEARCH 34:4569-4575(2014).
