MCL-1
-
Official Full Name
myeloid cell leukemia sequence 1 (BCL2-related) -
Overview
This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing. -
Synonyms
MCL-1;myeloid cell leukemia sequence 1 (BCL2-related);BCL2L3;Bcl-2-like protein 3;Bcl-2-related protein EAT/mcl1;mcl1/EAT;myeloid cell leukemia ES;induced myeloid leukemia cell differentiation protein Mcl-1;bcl2-L-3;MCL1L;MGC1839;myeloid cell leukemia sequence 1, isoform 1;MGC104264;TM;MCL1S;EAT;Bcl2-L-3
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|
Involved Pathway
MCL-1 involved in several pathways and played different roles in them. We selected most pathways MCL-1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MCL-1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
MCL-1 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by MCL-1 itself. We selected most functions MCL-1 had, and list some proteins which have the same functions with MCL-1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
MCL-1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MCL-1 here. Most of them are supplied by our site. Hope this information will be useful for your research of MCL-1.
Resources
Related Services
Related Products
References
