MAP1LC3B
-
Official Full Name
microtubule-associated protein 1 light chain 3 beta -
Overview
MAO1LC3B is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component. -
Synonyms
MAP1LC3B;microtubule-associated protein 1 light chain 3 beta;microtubule-associated proteins 1A/1B light chain 3B;ATG8F;MAP1A/MAP1B LC3 B;MAP1A/MAP1B light chain 3 B;MAP1 light chain 3-like protein 2;autophagy-related ubiquitin-like modifier LC3 B;LC3B;MAP1LC3B-a;MAP1A/1BLC3
Recombinant Proteins
- Human
- Zebrafish
- Rhesus macaque
- Chicken
- Rat
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- Yeast
- E. coli
- His
- GST
- Non
- His&MBP
- His&Fc&Avi
Involved Pathway
MAP1LC3B involved in several pathways and played different roles in them. We selected most pathways MAP1LC3B participated on our site, such as Cellular responses to stress,Macroautophagy,Mitophagy, which may be useful for your reference. Also, other proteins which involved in the same pathway with MAP1LC3B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Mitophagy | TOMM22,LC3,MFN2,TOMM7,MTERFD1,TOMM20B,TOMM5,TOMM20,TOMM40,TOMM6 |
| Macroautophagy | WIPI1,RB1CC1,ULK1A,AMBRA1,UVRAG,AMBRA1A,LC3,WDR45L,ATG4A,ATG9A |
| Pink/Parkin Mediated Mitophagy | TOMM40,LC3,TOMM70A,MFN1,TOMM6,TOMM22,TOMM20B,TOMM5,TOMM20,MTERFD1 |
| Cellular responses to stress | PRDX2,PTGES3,ATG9B,LAMTOR1,UVRAG,HBXIP,ACD,HIF3A,UBN1,RBB4L |
| Senescence and Autophagy | SLC39A3,AMBRA1,GABARAPL2,ING2,FKBP8,RB1CC1,GABARAP,ING1,RSL1D1,LC3 |
Protein Function
MAP1LC3B has several biochemical functions, for example, microtubule binding,protein binding,ubiquitin protein ligase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MAP1LC3B itself. We selected most functions MAP1LC3B had, and list some proteins which have the same functions with MAP1LC3B. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| microtubule binding | PRNP,MACF1,PAFAH1B1,KIF14,DPYSL2B,KIF4A,HOOK3,FMN1,KIAA1128,KIF3A |
| protein binding | SVIP,PPP1R9A,HELZ,ABHD16A,C10orf46,MEF2C,HNRNPR,EEF1A2,HJURP,PIBF1 |
| ubiquitin protein ligase binding | CDC34B,ACVR1B,NDUFS2,TCEB2,RPA3,BCL10,TMEM173,SNCAIP,CALR,BAG6 |
Interacting Protein
MAP1LC3B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAP1LC3B here. Most of them are supplied by our site. Hope this information will be useful for your research of MAP1LC3B.
SQSTM1;ATG4B
Resources
Related Services
Related Products
References
- Iqbal, O; Fisher, G; et al. Increased Expression of Secreted Frizzled-Related Protein-1 and Microtubule-Associated Protein Light Chain 3 in Keratoconus. CORNEA 32:702-707(2013).
- Sasaki, M; Miyakoshi, M; et al. Increased expression of mitochondrial proteins associated with autophagy in biliary epithelial lesions in primary biliary cirrhosis. LIVER INTERNATIONAL 33:312-320(2013).
