MAGEA4
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Official Full Name
melanoma antigen family A, 4 -
Overview
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. At least four variants encoding the same protein have been found for this gene. -
Synonyms
MAGEA4;melanoma antigen family A, 4;MAGE4;melanoma-associated antigen 4;cancer/testis antigen family 1;member 4;CT1.4;MAGE 41;MAGE X2;MAGE4A;MAGE4B;melanoma associated antigen 4;MGC21336;MAGE-4 antigen;MAGE-41 antigen;MAGE-X2 antigen;cance
Recombinant Proteins
- Human
- Rhesus macaque
- Mouse
- HEK293
- E.coli
- Mammalian Cells
- His
- Non
- Flag
- His&Myc
- His&Fc&Avi
- Myc&DDK
Involved Pathway
MAGEA4 involved in several pathways and played different roles in them. We selected most pathways MAGEA4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MAGEA4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
MAGEA4 has several biochemical functions, for example, molecular_function,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MAGEA4 itself. We selected most functions MAGEA4 had, and list some proteins which have the same functions with MAGEA4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | SRSF10,EIF4G1,CCNDBP1,TNPO2,ZFP36L1,ZRSR2,SPRY1,MPP5,PPARG,RTP4 |
| molecular_function | CYB5R1,ZFAND5,DEFB50,MARCH11,DISP2,ABHD2,GM13304,SPRY3,CCDC187,LANCL3 |
Interacting Protein
MAGEA4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAGEA4 here. Most of them are supplied by our site. Hope this information will be useful for your research of MAGEA4.
PSMD10;TRIM69;ZBTB17;POT1;UQCRB;TEKT4
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