MAGEA10
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Official Full Name
melanoma antigen family A, 10 -
Overview
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream melanoma antigen family A, 5 (MAGEA5) gene. -
Synonyms
MAGEA10;melanoma antigen family A, 10;MAGE10;melanoma-associated antigen 10;cancer/testis antigen family 1;member 10;CT1.10;MAGE 10 antigen;melanoma associated antigen 10;MGC10599;MAGE-10 antigen;cancer/testis antigen 1.10;cancer/testis antige
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| MAGEA10-689H | Recombinant Human MAGEA10, GST-tagged | E.coli | Human | GST | 39-369aa | |
| MAGEA10-2125HCL | Recombinant Human MAGEA10 cell lysate | Human | Non |
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| MAGEA10-2231H | Recombinant Human MAGEA10 Protein (1-369 aa), His-tagged | Yeast | Human | His | 1-369 aa |
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| MAGEA10-3198H | Recombinant Human MAGEA10 protein, His-tagged | E.coli | Human | His | 1-369aa |
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Involved Pathway
MAGEA10 involved in several pathways and played different roles in them. We selected most pathways MAGEA10 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MAGEA10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
MAGEA10 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by MAGEA10 itself. We selected most functions MAGEA10 had, and list some proteins which have the same functions with MAGEA10. You can find most of the proteins on our site.
| Function | Related Protein |
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Interacting Protein
MAGEA10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAGEA10 here. Most of them are supplied by our site. Hope this information will be useful for your research of MAGEA10.
PON2;XPO1;SCO2;NCOA2;QSER1;FAM216A;KAT2A;FOXJ2;SLAIN2;MTUS1;MTCL1
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References
- Uzdensky, A; Demyanenko, S; et al. Expression of proteins involved in epigenetic regulation in human cutaneous melanoma and peritumoral skin. TUMOR BIOLOGY 35:8225-8233(2014).
- Smethurst, D; et al. A pharmacologic perspective on newly emerging T-cell manipulation technologies. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY 76:173-187(2013).
