LSS
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Official Full Name
lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) -
Overview
The protein encoded by this gene catalyzes the conversion of (S)-2,3 oxidosqualene to lanosterol. The encoded protein is a member of the terpene cyclase/mutase family and catalyzes the first step in the biosynthesis of cholesterol, steroid hormones, and vitamin D. Alternative splicing results in multiple transcript variants encoding different isoforms. -
Synonyms
LSS;lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase);lanosterol synthase;OSC;hOSC;oxidosqualene--lanosterol cyclase;2,3-epoxysqualene-lanosterol cyclase;2,3-epoxysqualene--lanosterol cyclase;FLJ25486;FLJ35015;FLJ39450;FLJ46393
Recombinant Proteins
- Chicken
- Human
- Rat
- Zebrafish
- Mouse
- Staphylococcus simulans
- Mammalian Cells
- E.coli
- HEK293
- Wheat Germ
- His
- Non
- Myc&DDK
- His&Fc&Avi
- Flag
- GST
Involved Pathway
LSS involved in several pathways and played different roles in them. We selected most pathways LSS participated on our site, such as Steroid biosynthesis,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with LSS were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolic pathways | POLR2K,TAT,AGXTA,PDXKB,HYAL1,GAL3ST1,GATC,TBXAS1,AANAT,UGT1A6 |
| Steroid biosynthesis | SOAT1,CEL.1,SC4MOL,DHCR7,Cel,DHCR24,CYP2R1,HSD17B7,CYP51,MSMO1 |
Protein Function
LSS has several biochemical functions, for example, lanosterol synthase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by LSS itself. We selected most functions LSS had, and list some proteins which have the same functions with LSS. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
LSS has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LSS here. Most of them are supplied by our site. Hope this information will be useful for your research of LSS.
NR4A1;MYH9;FIP1L1;Klc2;MYO5C
Resources
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References
- Atwe, SU; Ma, YZ; et al. Pollen grains for oral vaccination. JOURNAL OF CONTROLLED RELEASE 194:45-52(2014).
- Turzhitsky, V; Qiu, L; et al. Spectroscopy of Scattered Light for the Characterization of Micro and Nanoscale Objects in Biology and Medicine. APPLIED SPECTROSCOPY 68:133-154(2014).
