LRP1

  • Official Full Name

    LRP1 low density lipoprotein receptor-related protein 1

  • Synonyms

    LRP1;low density lipoprotein receptor-related protein 1;A2MR, alpha 2 macroglobulin receptor , APR;prolow-density lipoprotein receptor-related protein 1;CD91;LRP;LRP-1;type V tgf-beta receptor;apolipoprotein E receptor;alpha-2-macroglobulin receptor;TbetaR-V/LRP-1/IGFBP-3 receptor;APR;A2MR;APOER;TGFBR5;IGFBP3R;FLJ16451;MGC88725

Recombinant Proteins

  • Human
  • Mouse
  • Chicken
  • CHO
  • HEK293
  • Human Cells
  • Mammalian Cells
  • E.coli
  • Human Plasma
  • Wheat Germ
  • In Vitro Cell Free System
  • Fc
  • His
  • Non
  • His&T7
  • GST&His
  • Avi&Fc&His
  • GST
Cat.# Product name Source (Host) Species Tag Protein Length Price
LRP1-654H Active Recombinant Human LRP1 protein, Fc-tagged CHO Human Fc 3332-3779 a.a.
LRP1-001H Recombinant Human LDL receptor related protein 1 Protein, His tagged HEK293 Human His 2522-2941 aa
LRP1-3357H Recombinant Human LRP1, None tagged Human Cells Human Non 786-1165 a.a.
LRP1-652H Active Recombinant Human LRP1 protein, Fc-tagged Mammalian Cells Human Fc 786-1165 a.a.
LRP1-653H Active Recombinant Human LRP1 protein, Fc-tagged CHO Human Fc 2522-2941 a.a.
LRP1-5720H Recombinant Human LRP1 protein, His-tagged E.coli Human His Val4441~Ala4544
Lrp1-5721M Recombinant Mouse Lrp1 protein, His & T7-tagged E.coli Mouse His&T7 Ile692~Cys962
Lrp1-5722M Recombinant Mouse Lrp1 protein, His & GST-tagged E.coli Mouse GST&His Lys337~Ala426
LRP1-6795C Recombinant Chicken LRP1 Mammalian Cells Chicken His
LRP1-2217HCL Recombinant Human LRP1 cell lysate Human Cells Human Non
LRP1-0361H Recombinant Human LRP1 protein, Fc-tagged HEK293 Human Fc 3332-3779 a.a.
LRP1-0362H Recombinant Human LRP1 protein, Fc-tagged HEK293 Human Fc 2522-2941 a.a.
LRP1-0677H Recombinant Human LRP1 Protein (Ala20-Gly292), N-His tagged E.coli Human His Ala20-Gly292
LRP1-0712H Recombinant Human LRP1 Protein (Ala20-His280), N-His tagged E.coli Human His Ala20-His280
LRP1-121H Recombinant Human LRP1 Protein, His (Fc)-Avi-tagged HEK293 Human Avi&Fc&His
LRP1-121H-B Recombinant Human LRP1 Protein Pre-coupled Magnetic Beads HEK293 Human
LRP1-18H Native Human Intermediate Density Lipoproteins Protein Human Plasma Human Non
LRP1-2404H Recombinant Human LRP1 Protein, His-tagged E.coli Human His Ala20-Asp429
LRP1-3356H Active Recombinant Human LRP1 protein, Fc-tagged HEK293 Human Fc Arg 786 - Leu 1165
LRP1-4697H Recombinant Human LRP1 Protein, GST-tagged Wheat Germ Human GST
LRP1-4698H Recombinant Human LRP1 Protein Wheat Germ Human Non
LRP1-6010HF Recombinant Full Length Human LRP1 Protein In Vitro Cell Free System Human Full L. 372 amino acids
LRP1-6011HF Recombinant Full Length Human LRP1 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 292 amino acids
LRP1-87H Native Human Lipoproteins Human Plasma Human Non

    Involved Pathway

    LRP1 involved in several pathways and played different roles in them. We selected most pathways LRP1 participated on our site, such as Alzheimers disease,Malaria, which may be useful for your reference. Also, other proteins which involved in the same pathway with LRP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Malaria CD36,CCL2,CSF3,DARC,GYPA,TGFB1,TNF,IL1B,THBS2,HBA2
    Alzheimers disease NDUFA5,NDUFC1,CASP9,ITPR2,UQCRB,BID,AKR1C1,NCSTN,PPP3CC,UQCR10

    Protein Function

    LRP1 has several biochemical functions, for example, apolipoprotein binding,calcium ion binding,lipoprotein particle receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LRP1 itself. We selected most functions LRP1 had, and list some proteins which have the same functions with LRP1. You can find most of the proteins on our site.

    Function Related Protein
    receptor activity VMN1R43,THBD,CSF2RA,OPN1SW,TLR4,NEO1,LYVE1,VMN1R54,TNFRSF10B,KIR2DL1
    apolipoprotein binding LRP6,LIPC,PLG,CANX,SCARB1,PCSK9,ABCA1,VLDLR,LPA,MAPT
    lipoprotein particle receptor binding APOA5,Reln
    protein binding PHIP,EMX2,ABCG2,RFWD3,FOXK1,S100A10,ADCK5,TAF1C,INTS4,SPPL3
    calcium ion binding TNNC2,DLL1,ANXA10,CAPN1B,SPOCK1,NCALDB,CDH15,GM5077,C2CD4A,FLG2
    protease binding CST3,CCDC71L,F3,COMP,MALT1,ALPI,IL1R1,NDUFS7,TIMP2A,CCBE1
    poly(A) RNA binding HLTF,MKRN2,RPS16,MRPL44,WDR46,CANX,GLTSCR2,RPL37A,KHSRP,CCDC47
    protein complex binding CEBPA,VPS28,AP2A1,SLC27A5,RAN,SLC25A3,CAPG,TAPBPL,RPTOR,CDK5RAP1

    Interacting Protein

    LRP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LRP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of LRP1.

    APBB1;MBL2;FCN2;Thbs2;Jag1;SRC;dimyristoylphosphatidyl choline

    Resources

    Research Area

    Serine Proteases and Regulators
    Lipoprotein Receptors and Associated Proteins
    Uptake and Transport Molecules in VSMC
    Blood-brain Barrier Transporters
    Wnt Receptors
    Macrophage Markers
    Monocyte Markers
    Scavenger Receptors

    References

    • Regina, A; Demeule, M; et al. ANG4043, a Novel Brain-Penetrant Peptide-mAb Conjugate, Is Efficacious against HER2-Positive Intracranial Tumors in Mice. MOLECULAR CANCER THERAPEUTICS 14:129-140(2015).
    • Mei, L; Zhang, QY; et al. Angiopep-2 and activatable cell penetrating peptide dual modified nanoparticles for enhanced tumor targeting and penetrating. INTERNATIONAL JOURNAL OF PHARMACEUTICS 474:95-102(2014).

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