LCMT1
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Official Full Name
leucine carboxyl methyltransferase 1 -
Overview
LCMT1 catalyzes the methylation of the carboxyl group of the C-terminal leucine residue (leu309) of the catalytic;subunit of protein phosphatase-2A (PPP2CA; MIM 176915) (De Baere et al., 1999 (PubMed 10600115)). -
Synonyms
LCMT1;leucine carboxyl methyltransferase 1;Lcmt;LCMT-1;AL033290;MGC11807
Recombinant Proteins
- Human
- Chicken
- Zebrafish
- Rhesus macaque
- Rat
- Cynomolgus
- Mouse
- Insect Cells
- Mammalian Cells
- E.coli
- HEK293
- GST
- His
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
LCMT1 involved in several pathways and played different roles in them. We selected most pathways LCMT1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with LCMT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
LCMT1 has several biochemical functions, for example, S-adenosylmethionine-dependent methyltransferase activity,protein C-terminal carboxyl O-methyltransferase activity,protein C-terminal leucine carboxyl O-methyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by LCMT1 itself. We selected most functions LCMT1 had, and list some proteins which have the same functions with LCMT1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| S-adenosylmethionine-dependent methyltransferase activity | TPMT.2,MEPCE,RRP8,ASMT2,LCMT2,PRMT8B,WBSCR27,COQ5,AS3MT,LSM1 |
| protein C-terminal carboxyl O-methyltransferase activity | RNMTL1A,PRDM11,RNMTL1B,PRDM13,PRDM12,PRMT8B,FBLL1,METTL23,FAM86,METTL21A |
| protein binding | CTRC,PDCD6,LIMK1,TSPO,H1F0,MECOM,SRSF10,ESR2,FOXR1,RSPO1 |
| protein C-terminal leucine carboxyl O-methyltransferase activity | METTL21D,PRDM13,FBLL1,PRDM11,NDUFAF5,METTL8,TRMT10C,DIMT1,FAM86,METTL7B |
Interacting Protein
LCMT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LCMT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of LCMT1.
FXR2;solA;TAB1
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References
- Longin, S; Zwaenepoel, K; et al. Spatial control of protein phosphatase 2A (de)methylation. EXPERIMENTAL CELL RESEARCH 314:68-81(2008).
