LAMA1
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Official Full Name
laminin, alpha 1 -
Overview
Laminin subunit alpha-1 is a protein that in humans is encoded by the LAMA1 gene. -
Synonyms
LAMA1;laminin, alpha 1;LAMA;laminin subunit alpha-1;S-LAM alpha;laminin A chain;S-laminin subunit alpha;laminin-3 subunit alpha;S-LAM-alpha
Recombinant Proteins
- Human
- Mouse
- Rat
- Zebrafish
- Chicken
- E.coli
- Mammalian Cells
- HEK293
- His
- His&T7
- Fc
- GST
- His&Fc&Avi
- His&GST
- His&SUMO
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| LAMA1-2589H | Recombinant Human LAMA1 protein, His-tagged | E.coli | Human | His | Ala886~Val1039 |
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| LAMA1-258H | Recombinant Human LAMA1 | Mammalian Cells | Human | His |
|
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| LAMA1-2590H | Recombinant Human LAMA1 protein, His-tagged | E.coli | Human | His | Val2613~Phe2746 |
|
| Lama1-2591M | Recombinant Mouse Lama1 protein, His-tagged | E.coli | Mouse | His | Thr2640~Thr2773 |
|
| Lama1-2592R | Recombinant Rat Lama1 protein, His & T7-tagged | E.coli | Rat | His&T7 | His41~Tyr230 |
|
| Lama1-2593R | Recombinant Rat Lama1 protein, His & T7-tagged | E.coli | Rat | His&T7 | Pro1156~Ile1276 |
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| LAMA1-3461Z | Recombinant Zebrafish LAMA1 | Mammalian Cells | Zebrafish | His |
|
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| LAMA1-4475C | Recombinant Chicken LAMA1 | Mammalian Cells | Chicken | His |
|
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| LAMA1-0326H | Active Recombinant Human LAMA1 protein, Fc-tagged | HEK293 | Human | Fc | 1878-2700;1573-1798 a.a. |
|
| LAMA1-0345H | Active Recombinant Human LAMA1 protein, Fc-tagged | HEK293 | Human | Fc | 1878-2700 a.a. |
|
| LAMA1-301469H | Recombinant Human LAMA1 protein, GST-tagged | E.coli | Human | GST | Ser1592-Ser1778 |
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| LAMA1-30170H | Recombinant Human LAMA1 protein, His-tagged | E.coli | Human | His | 1592-1778 aa |
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| LAMA1-3328H | Recombinant Human LAMA1 Protein, His (Fc)-Avi-tagged | HEK293 | Human | His&Fc&Avi |
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| LAMA1-3328H-B | Recombinant Human LAMA1 Protein Pre-coupled Magnetic Beads | HEK293 | Human |
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| LAMA1-3340H | Recombinant Human LAMA1 protein, His-GST-tagged | E.coli | Human | His&GST | Ala886~Val1039 |
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| LAMA1-3341H | Recombinant Human LAMA1 protein, His-SUMO-tagged | E.coli | Human | His&SUMO | Ala886~Val1039 |
|
Involved Pathway
LAMA1 involved in several pathways and played different roles in them. We selected most pathways LAMA1 participated on our site, such as PIK-Akt signaling pathway,Focal adhesion,ECM-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with LAMA1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Toxoplasmosis | TNF,LAMB4,LAMC1,HLA-DRB4,MAP2K3,HSPA1A,HLA-DMA,MAPK9,IL10RA,NFKB1 |
| Amoebiasis | LAMB2,IL10,CD1D,SERPINB3C,ITGAM,SERPINB3,SERPINB1,CTSG,RAB7,ARG2 |
| Small cell lung cancer | AKT2,TRAF2,TRP53,CCNE2,BIRC8,IKBKG,NOS2,ITGA6,PIK3CB,APAF1 |
| ECM-receptor interaction | COL11A1A,ITGA11A,COL4A5,GP9,ITGB7,ITGA6B,ITGB8,ITGA4,COMP,COL6A3 |
| PIK-Akt signaling pathway | FGFR1,KIT,THBS3,ATF4,BAD,RPS6KB1,Ifna11,PKN1,INS1,GNG12 |
| Pathways in cancer | GNG5,ITGB1,FIGF,FGF2,NKX3-1,BCR,ITGA2,GNG8,STK36,IL6 |
| Focal adhesion | CAPN2A,ITGB3,ACTN1,BCAR1,IBSP,AKT1,MYL12.2,VAV2,CAPN2L,TESK2 |
Protein Function
LAMA1 has several biochemical functions, for example, extracellular matrix structural constituent,glycosphingolipid binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LAMA1 itself. We selected most functions LAMA1 had, and list some proteins which have the same functions with LAMA1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | KCNB1,P4HA3,ZNF263,C2orf62,TMEM149,SMAGP,NLRC4,CCDC53,MPL,FBXO3 |
| receptor binding | TNFSF13B,PTK6B,PECI,SELPLG,AKAP9,NPFF,NPFFL,FGF6A,LHB,CCL17 |
| glycosphingolipid binding | Cel,LYN,LAMB1,LAMC1,SELP,Il2,SELL |
| extracellular matrix structural constituent | PRELP,LUM,COL4A5,COL2A1A,MATN1,COL27A1,COMP,MEPE,COL11A1A,COL27A1B |
Interacting Protein
LAMA1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LAMA1 here. Most of them are supplied by our site. Hope this information will be useful for your research of LAMA1.
p4c;CBX4;BAG3;TOMM40;HSPA5;Myh3;TUBG1;MAPK9;NES;Tubg1;STRN3;LAMB3;Prkci;Prmt6;Immt;Dctn4;Trim32;ATL2;Kctd5
Resources
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References
- Paez, MC; Matsuura, E; et al. Laminin-1 (LM-111) in preeclampsia and systemic lupus erythematosus. AUTOIMMUNITY 46:14-20(2013).
- Igarashi, T; Tajiri, Y; et al. Tubulointerstitial Nephritis Antigen-Like 1 Is Expressed in Extraembryonic Tissues and Interacts with Laminin 1 in the Reichert Membrane at Postimplantation in the Mouse. BIOLOGY OF REPRODUCTION 81:948-955(2009).
