KLK12
-
Official Full Name
kallikrein-related peptidase 12 -
Overview
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in three transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] -
Synonyms
KLK12;kallikrein-related peptidase 12;KLKL5;KLK-L5;kallikrein-12;kallikrein 12;kallikrein-like protein 5
Recombinant Proteins
- Human
- Mammalian Cells
- E.coli
- HEK293
- His
- His&T7
- Non
- His&Fc&Avi
- N-His&C-Myc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| KLK12-1977H |
Active Recombinant Human Kallikrein-Related Peptidase 12, His-tagged
|
Mammalian Cells | Human | His | 18-248 a.a. |
|
| KLK12-834H |
Active Recombinant Human KLK12 Protein, His-tagged
|
Mammalian Cells | Human | His | Ala18-Asn248 |
|
| KLK12-7998H | Recombinant Human KLK12 protein, His & T7-tagged | E.coli | Human | His&T7 | Ala18~Asn248 |
|
| KLK12-4903HCL | Recombinant Human KLK12 293 Cell Lysate | HEK293 | Human | Non |
|
|
| KLK12-3229H | Recombinant Human KLK12 Protein, His (Fc)-Avi-tagged | HEK293 | Human | His&Fc&Avi |
|
|
| KLK12-3229H-B | Recombinant Human KLK12 Protein Pre-coupled Magnetic Beads | HEK293 | Human |
|
||
| KLK12-4602H | Recombinant Human KLK12 Protein (Ala18-Asn248), N-His tagged | E.coli | Human | His | Ala18-Asn248 |
|
| KLK12-7648H | Recombinant Human KLK12 protein(18-248aa), His&Myc-tagged | E.coli | Human | N-His&C-Myc | 18-248aa |
|
Involved Pathway
KLK12 involved in several pathways and played different roles in them. We selected most pathways KLK12 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with KLK12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
KLK12 has several biochemical functions, for example, peptidase activity,serine-type endopeptidase activity,serine-type peptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KLK12 itself. We selected most functions KLK12 had, and list some proteins which have the same functions with KLK12. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| serine-type peptidase activity | Gzmg,PARLA,DPP6B,IRBP,GZMM,GM5077,TMPRSS7,HTRA2,KLK1B1,PLAUB |
| peptidase activity | MMP25,GZMC,C1rb,HE2,CAPN5A,CAPN12,CLCA3,PRSS44,KLK1B9,AGBL4 |
| serine-type endopeptidase activity | LOC780933,PROC,KLK4,PROCA,KLK1B9,LOC100686744,TMPRSS5,CORIN,CELA2B,F11 |
Interacting Protein
KLK12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KLK12 here. Most of them are supplied by our site. Hope this information will be useful for your research of KLK12.
Resources
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References
- El Annan, J; Jiang, GM; et al. Elevated Immunoglobulin to Tissue KLK11 in Patients With Sjogren Syndrome. CORNEA 32:E90-E93(2013).
- Memari, N; Diamandis, EP; et al. Human kallikrein-related peptidase 12: Antibody generation and immunohistochemical localization in prostatic tissues. PROSTATE 67:1465-1474(2007).
