KCNK9
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Official Full Name
potassium channel, subfamily K, member 9 -
Overview
This gene encodes a member of the superfamily of potassium channel proteins containing two pore-forming P domains, and is highly expressed in the cerebellum. Amplification and overexpression of this gene has been observed in several types of human carcinomas, notably in breast cancer. This gene is imprinted in fetal brain, with preferential expression from the maternal allele. -
Synonyms
KCNK9;potassium channel, subfamily K, member 9;potassium channel subfamily K member 9;K2p9.1;TASK 3;TASK3;Acid sensitive potassium channel protein TASK 3;KT3.2;Potassium channel TASK3;Potassium channel, subfamily K, member 9 (TASK 3);TWIK related acid sensitive K+ channel 3;OTTHUMP00000226147;two pore K(+) channel KT3.2;two pore potassium channel KT3.2;TWIK-related acid-sensitive K+ channel 3;TWIK-related acid-sensitive K(+) channel 3;acid-sensitive potassium cha;TASK-3
Recombinant Proteins
- Rat
- Zebrafish
- Mouse
- Human
- Mus musculus
- Xenopus laevis
- Guinea pig
- Mammalian Cells
- E.coli
- HEK293
- His
- His&Fc&Avi
- Non
Involved Pathway
KCNK9 involved in several pathways and played different roles in them. We selected most pathways KCNK9 participated on our site, such as Aldosterone synthesis and secretion, which may be useful for your reference. Also, other proteins which involved in the same pathway with KCNK9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Aldosterone synthesis and secretion | ADCY3,ADCY8,CAMK2B,PRKD1,HSD3B6,GNAS,NR4A1,HSD3B5,AGTR1B,CREB3L1 |
Protein Function
KCNK9 has several biochemical functions, for example, potassium channel activity,potassium ion leak channel activity,protein heterodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KCNK9 itself. We selected most functions KCNK9 had, and list some proteins which have the same functions with KCNK9. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| potassium channel activity | KCNC1B,KCNK5B,KCNK1A,KCNQ3,KCNG4A,TRPM5,KCNC2,KCNC1A,KCNK1B,KCNH5 |
| protein homodimerization activity | RNF40,XPNPEP1,SLC16A1,SYT10,HES1,TARS,TYRP1,MYH7,ZNF174,WRN |
| voltage-gated potassium channel activity | KCNC3A,KCNAB2B,KCNH1A,KCNB2,KCNJ11,KCNC1B,CNGA1,KCNV2B,KCNQ1,KCNH5A |
| protein heterodimerization activity | EGFR,KCNK3,ZHX2,NEFH,SCGB2A1,IKZF3,NOTCH1,CUL3,BAX,TP53 |
| potassium ion leak channel activity | KCNK13B,KCNK10,KCNK15,KCNK2,KCNK4,KCNK2B,KCNK5B,KCNK7,KCNK13A,KCNK5A |
Interacting Protein
KCNK9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KCNK9 here. Most of them are supplied by our site. Hope this information will be useful for your research of KCNK9.
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