KCNJ3
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Official Full Name
Kcnj3 potassium inwardly-rectifying channel, subfamily J, member 3 -
Synonyms
KCNJ3;potassium inwardly-rectifying channel, subfamily J, member 3;G protein-activated inward rectifier potassium channel 1;GIRK-1;inward rectifier K(+) channel Kir3.1;potassium inwardly-rectifying channel J3;potassium channel, inwardly rectifying subfamily J member 3;GIRK1;Kcnf3;Kir3.1;MGC124233;MGC124234
Recombinant Proteins
- Rhesus macaque
- Rat
- Chicken
- Mouse
- Human
- Mus musculus
- Mammalian Cells
- HEK293
- E.coli
- His
- Non
- His&Fc&Avi
Involved Pathway
KCNJ3 involved in several pathways and played different roles in them. We selected most pathways KCNJ3 participated on our site, such as Activation of G protein gated Potassium channels,Activation of GABAB receptors,Calcium Regulation in the Cardiac Cell, which may be useful for your reference. Also, other proteins which involved in the same pathway with KCNJ3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cholinergic synapse | PLCB4,AKR1C1,CREB3L2,GNAO1,MAPK1,GNAI3,PRKCG,MAPK3,FOS,GNG4 |
| Estrogen signaling pathway | MAP2K1,NRAS,PIK3CD,ITPR1,HSP90AB1,HSP90AA1,ESR2,SHC3,ATF6B,AKT2 |
| Dopaminergic synapse | GNAI3,CREB5,GSK3B,FOS,PPP2CB,GNG7,DRD1,GRIA4,PLCB4,KIF5B |
| Calcium Regulation in the Cardiac Cell | PKIG,FKBP1A,CASQ1,GNB3B,RGS11,CX35.4,RGS14,GJA3,GNG13B,CHRM3 |
| G Protein Signaling Pathways | AKAP12B,AKAP8,GNB3B,AKAP12,AKAP7,GNGT2A,GNG13B,Akap2,GNB5B,ARHGEF1A |
| Activation of GABAB receptors | GNB3A,GNGT2B,ADCY8,KCNJ9,ADCY3,KCNJ12,KCNJ4,KCNJ5,GNGT2A,KCNJ15 |
| Circadian entrainment | GRIN2A,GNAO1,CAMK2D,RPS6KA5,PRKCA,GRIN1,GUCY1B3,GNG8,FOS,GNB2 |
| Activation of G protein gated Potassium channels | KCNJ2A,KCNJ10,GNB3A,KCNJ9,KCNJ2,KCNJ6,GNGT2A,GNGT2B,KCNJ4,GNB3B |
Protein Function
KCNJ3 has several biochemical functions, for example, G-protein activated inward rectifier potassium channel activity,contributes_to inward rectifier potassium channel activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KCNJ3 itself. We selected most functions KCNJ3 had, and list some proteins which have the same functions with KCNJ3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| G-protein activated inward rectifier potassium channel activity | KCNJ5,KCNJ6,KCNJ9 |
| protein binding | CUTA,CCDC64B,RALBP1,MERTK,COL13A1,LMNA,LAMA4,PFDN5,SPRY4,WHSC1L1 |
| contributes_to inward rectifier potassium channel activity | KCNJ5,KCNE2 |
Interacting Protein
KCNJ3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KCNJ3 here. Most of them are supplied by our site. Hope this information will be useful for your research of KCNJ3.
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References
- Langford, DJ; Paul, SM; et al. Variations in potassium channel genes are associated with distinct trajectories of persistent breast pain after breast cancer surgery. PAIN 156:371-380(2015).
- Amaral, AC; Jakovcevski, M; et al. PRENATAL PROTEIN MALNUTRITION DECREASES KCNJ3 AND 2DG ACTIVITY IN RAT PREFRONTAL CORTEX. NEUROSCIENCE 286:79-86(2015).
