INSIG2
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Official Full Name
insulin induced gene 2 -
Synonyms
Insig-2;2900053I11Rik;C730043J18Rik
Recombinant Proteins
- Zebrafish
- Rhesus macaque
- Chicken
- Rat
- Human
- Mouse
- Sus scrofa (Pig)
- Papio anubis (Olive baboon)
- Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
- Pongo Abelii
- Xenopus laevis
- Callithrix jacchus (White-tufted-ear marmoset)
- Mus musculus
- Mammalian Cells
- HEK293
- Protein Conjugation
- E.coli
- Wheat Germ
- In Vitro Cell Free System
- His
- Non
- His&Fc&Avi
- Flag
- Myc&DDK
- His&Myc
- GST
Involved Pathway
INSIG2 involved in several pathways and played different roles in them. We selected most pathways INSIG2 participated on our site, such as Metabolism,Metabolism of lipids and lipoproteins,Regulation of cholesterol biosynthesis by SREBP (SREBF), which may be useful for your reference. Also, other proteins which involved in the same pathway with INSIG2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolism of lipids and lipoproteins | FABP1B.1,MTF1,SLC27A2A,PITPNB,SPTLC1,AGPAT6,ARF3,ABHD4,GLTPD1,SUMF2 |
| SREBP signalling | SEC23B,INSIG1,RBP4,DBI,RNF139 |
| Metabolism | OAZ3,ADK,ACOT6,DTYMK,HIBADH,PYGMB,SLC2A3,NOSTRIN,CIAPIN1,MED15 |
| Regulation of cholesterol biosynthesis by SREBP (SREBF) | PMVK,SREBF2,INSIG1,DHCR7,NFYBA,NFYBB,NFYAL,YY2,MTF1 |
Protein Function
INSIG2 has several biochemical functions, for example, protein binding,transcription factor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by INSIG2 itself. We selected most functions INSIG2 had, and list some proteins which have the same functions with INSIG2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | KIAA0101,DDC,LATS2,MAGEA2,IDE,SEC22A,VPS37B,DGCR6L,NFKBIB,NUDC |
| transcription factor binding | GPX3,CRY1,TBX5,PRKDC,CEBPA,CDKN2A,GTF2F1,PPP1R13L,RORA,PAX6 |
Interacting Protein
INSIG2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with INSIG2 here. Most of them are supplied by our site. Hope this information will be useful for your research of INSIG2.
RNF5;SEC27;copa_schpo;COP1
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