IL10RB
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Official Full Name
interleukin 10 receptor, beta -
Overview
The protein encoded by this gene belongs to the cytokine receptor family. It is an accessory chain essential for the active interleukin 10 receptor complex. Coexpression of this and IL10RA proteins has been shown to be required for IL10-induced signal transduction. This gene and three other interferon receptor genes, IFAR2, IFNAR1, and IFNGR2, form a class II cytokine receptor gene cluster located in a small region on chromosome 21. -
Synonyms
IL10RB;interleukin 10 receptor, beta;CRFB4, D21S58, D21S66;interleukin-10 receptor subunit beta;CDW210B;CRF2 4;IL 10R2;Cd210;CRF2-4;CRFB4;Cytokine receptor class II;Cytokine receptor class II CRF2 4;Cytokine receptor class-II member 4;Cytokine receptor family 2 member 4;Cytokine receptor family II member 4;D21S58;D21S66;I10R2_HUMAN;IL-10 receptor subunit beta;IL-10R subunit 2;IL-10R subunit beta;IL-10R2;IL-10RB;IL10R2;Interleukin 10 receptor beta;Interleukin-10 receptor subunit 2;OTTHUMP00000067678;cytokine receptor class-II CRF2-4;cytokine receptor fami
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- Chicken
- Rat
- CHO
- E.coli
- HEK293
- Mouse myeloma cell
- Mammalian Cells
- Human Cells
- Insect Cells
- Fc
- His
- Avi&Fc&His
- Fc&His
- Non
Involved Pathway
IL10RB involved in several pathways and played different roles in them. We selected most pathways IL10RB participated on our site, such as Cytokine-cytokine receptor interaction,Epstein-Barr virus infection,Jak-STAT signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with IL10RB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Type III interferon signaling | IL28RA,IRX1 |
| Cytokine-cytokine receptor interaction | IFNW1,Cxcl15,TNFRSF19,TNFRSF10B,Il23a; Il12b,IL2RA,CCL15,KITA,Il2,Ccl27a |
| Tuberculosis | PPP3CC,MRC2,MAPK11,NFYA,Il23a; Il12b,CAMK2G,MRC1,CALM3,HLA-DQB1,ATP6V0A1 |
| Jak-STAT signaling pathway | IL24,Il2,PIAS4B,IL12B,RAF1A,Il6ra,HRASB,IL13RA1,EP300,PTPN2A |
| Epstein-Barr virus infection | Fcer2a,RAN,SPI1,HLA-A,RELB,PIK3CA,NEDD4,CD38,HSPA1A,IRF3 |
| Toxoplasmosis | LAMB1,HLA-DMA,MAPK1,HLA-DQA2,CD40LG,PIK3CB,PIK3R1,NFKBIA,MYD88,AKT1 |
Protein Function
IL10RB has several biochemical functions, for example, contributes_to interleukin-10 receptor activity,protein binding,receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by IL10RB itself. We selected most functions IL10RB had, and list some proteins which have the same functions with IL10RB. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | NUDT22,FADD,CSF3R,RAB18,PARP9,PAX8,CRK,SIRT7,PRRG2,HOXB7 |
| receptor activity | APLNR,CD200R4,OGFRL2,CCR6,TLR6,VMN1R44,CD33,PAQR5B,NRP2,AMHR2 |
Interacting Protein
IL10RB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL10RB here. Most of them are supplied by our site. Hope this information will be useful for your research of IL10RB.
IL10RB Related Signal Pathway
Resources
Research Area
NeuroinflammationNatural Killer (NK) Cell CD Antigen
Negative Regulators of the Jak/STAT Pathway
Receptors in the Jak/STAT Pathway
Monocyte Marker CD Antigen
Other Monocytes/Macrophages CD Antigen
CD Antigen (Helper T Cells)
Monocyte Markers
T Follicular Helper (Tfh) Cells
IL-10 Family Receptors
Related Services
Related Products
References
