IFNL1
-
Official Full Name
interferon, lambda 1 -
Overview
This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 28B (IL28B) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). -
Synonyms
Cytokine ZCYTO21;IFN lambda 1;IFN-lambda-1;IFNL1;IL-29;IL29;IL29_HUMAN;Interferon lambda 1;Interferon lambda-1;Interleukin-29;interferon, lambda 1
Recombinant Proteins
- Human
- Rat
- Insect Cells
- HEK293
- E.coli
- NS0
- Human Cells
- Mammalian Cells
- His
- Non
- His&T7
- StrepII
- His&GST
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| IFNL1-01H | Recombinant Human IFNL1 Protein, His-tagged | Insect Cells | Human | His | 20-200 a.a. | |
| IFNL1-458H |
Active Recombinant Human IFNL1 Protein
|
HEK293 | Human | Non | 1-200 a.a. |
|
| IFNL1-945H |
Active Recombinant Human IFNL1 Protein
|
E.coli | Human | Non |
|
|
| IFNL1-02H |
Active Recombinant Human IFNL1 Protein, His-tagged
|
NS0 | Human | His | 20-200 a.a. |
|
| IFNL1-2126H | Recombinant Human IFNL1 protein, His & T7-tagged | E.coli | Human | His&T7 | Gly20~Thr200 |
|
| IFNL1-299H | Recombinant Human IFNL1, StrepII-tagged | Human Cells | Human | StrepII | 20-200, 181 a.a. |
|
| IFNL1-7733H | Recombinant Human IFNL1 | Human | Non |
|
||
| IFNL1-2007HCL | Recombinant Human IFNL1 cell lysate | Human Cells | Human | Non |
|
|
| IFNL1-118H | Recombinant Human IFNL1 Protein | E.coli | Human |
|
||
| IFNL1-120H | Recombinant Active Human IFNL1 Protein, His-tagged(C-ter) | E.coli | Human | His |
|
|
| Ifnl1-1653R | Recombinant Rat Ifnl1 Protein, His&GST-tagged | E.coli | Rat | His&GST | Thr25-Ala192 |
|
| IFNL1-17H | Active Recombinant Human IFNL1 Protein | E.coli | Human | 178 amino acids |
|
|
| Ifnl1-2771R | Recombinant Rat Ifnl1 Protein, His-tagged | HEK293 | Rat | His | Thr25-Ala192 |
|
| IFNL1-349HG | Active GMP Recombinant Human IFNL1 protein | HEK293 | Human | DNA sequence encoding Human IFN-λ1(NP_742152.1) was expressed with His tag at the C-terminal. |
|
|
| IFNL1-3689H | Recombinant Human IFNL1 Protein (Gly20-Thr200), His tagged | E.coli | Human | His | Gly20-Thr200 |
|
| IFNL1-3816H | Recombinant Human IFNL1 Protein (Met1-Thr200), C-His tagged | Mammalian Cells | Human | His | Met1-Thr200 |
|
| IFNL1-983H | Recombinant Human IFNL1 Protein, His-tagged | HEK293 | Human | His | Gly20-Thr200 |
|
Involved Pathway
IFNL1 involved in several pathways and played different roles in them. We selected most pathways IFNL1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with IFNL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
IFNL1 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by IFNL1 itself. We selected most functions IFNL1 had, and list some proteins which have the same functions with IFNL1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
IFNL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IFNL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of IFNL1.
Resources
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References
- Egli, A; Santer, DM; et al. IL-28B is a Key Regulator of B- and T-Cell Vaccine Responses against Influenza. PLOS PATHOGENS 10:-(2014).
- Guedj, J; Rotman, Y; et al. Understanding Early Serum Hepatitis D Virus and Hepatitis B Surface Antigen Kinetics During Pegylated Interferon-alpha Therapy Via Mathematical Modeling. HEPATOLOGY 60:1902-1910(2014).
