IDO2
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Official Full Name
indoleamine 2,3-dioxygenase 2
Recombinant Proteins
- Human
- Mouse
- Rat
- E.coli
- HEK293
- Yeast
- Mammalian cells
- HEK293T
- His
- Myc&DDK
- Non
- His&Fc&Avi
- Flag
- His&SUMO
Involved Pathway
IDO2 involved in several pathways and played different roles in them. We selected most pathways IDO2 participated on our site, such as African trypanosomiasis,Histidine, lysine, phenylalanine, tyrosine, proline and tryptophan catabolism,L-kynurenine degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with IDO2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Tryptophan catabolism | AFMID |
| L-kynurenine degradation | AFMID,ACMSD |
| Metabolism of amino acids and derivatives | OAZ2B,PCBD1,NQO1,TPH2,SLC6A7,SLC6A8,AMD2,HIBADHA,NAGS,LSM1 |
| Histidine, lysine, phenylalanine, tyrosine, proline and tryptophan catabolism | PCBD1,UROC1,FTCD,ACMSD,SLC25A21,AMDHD1,CRYM,DLST,AFMID |
| Metabolic pathways | ATP6V1C1B,RPIA,SQLEA,CYP19A1,GGT5,MGAT5B,GLCE,LPIN3,DHRS4L2,PIK3C2B |
| African trypanosomiasis | HBA1,HPR,IFNG,F2RL1,APOL1,HBA2,VCAM1,IL18,IL10,PLCB4 |
| Metabolism | TREH,MED25,GLYAT,SLC35B3,PCBD1,AKR1C21,PDK3,MAPK1IP1L,DHCR7,Gpc2 |
| NAD de novo biosynthesis | AFMID |
Protein Function
IDO2 has several biochemical functions, for example, heme binding,indoleamine 2,3-dioxygenase activity,metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IDO2 itself. We selected most functions IDO2 had, and list some proteins which have the same functions with IDO2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| tryptophan 2,3-dioxygenase activity | TDO2A,TDO2,TDO2B,IDO1 |
| metal ion binding | ZNF800,POMT2,ZBTB20,FTR14,GEN1,CLCA2,ZFPM2A,ZBTB14,CYP19A1B,IMPDH1 |
| indoleamine 2,3-dioxygenase activity | IDO1 |
| heme binding | CYP20A1,HBBE1.1,STC2,CYP4F22,HRG-1,FAM84B,NOS3,HBA2,CYP3A43,NOX4 |
Interacting Protein
IDO2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IDO2 here. Most of them are supplied by our site. Hope this information will be useful for your research of IDO2.
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