IDI1
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Official Full Name
isopentenyl-diphosphate delta isomerase 1 -
Overview
IDI1 encodes a peroxisomally-localized enzyme that catalyzes the interconversion of isopentenyl diphosphate (IPP) to its highly electrophilic isomer, dimethylallyl diphosphate (DMAPP), which are the substrates for the successive reaction that results in the synthesis of farnesyl diphosphate and, ultimately, cholesterol.It has been shown in peroxisomal deficiency diseases such as Zellweger syndrome and neonatal adrenoleukodystrophy that there is reduction in IPP isomerase activity. -
Synonyms
IDI1;isopentenyl-diphosphate delta isomerase 1;isopentenyl diphosphate delta isomerase;isopentenyl-diphosphate Delta-isomerase 1;IPP isomerase;IDI1_HUMAN;IPP isomerase 1;IPPI1;Isopentenyl diphosphate Delta isomerase 1;isopentenyl diphosphate dimethylallyl diphosphate isomerase 1;Isopentenyl pyrophosphate isomerase 1;OTTHUMP00000018949;OTTHUMP00000018951;IPP1
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| IDI1-14052H | Recombinant Human IDI1, GST-tagged | E.coli | Human | GST | C-term-237a.a. | |
| IDI1-1527H | Recombinant Human Isopentenyl-Diphosphate Isomerase 1, His-tagged | Human | Human | His |
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| IDI1-26060TH | Recombinant Human IDI1, His-tagged | E.coli | Human | His | 228 amino acids |
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| IDI1-3111Z | Recombinant Zebrafish IDI1 | Mammalian Cells | Zebrafish | His |
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| IDI1-834HCL | Recombinant Human IDI1 cell lysate | Human | Non |
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| CBCRY10 | Isopentenyl-diphosphate delta-isomerase 1 | E.coli | Non |
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Involved Pathway
IDI1 involved in several pathways and played different roles in them. We selected most pathways IDI1 participated on our site, such as Terpenoid backbone biosynthesis,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with IDI1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolic pathways | LTA4H,HDC,PAPSS2B,GALNT7,GMPPB,HSD11B1,GALE,udp,ADC,DPAGT1 |
| Terpenoid backbone biosynthesis | HMGCR,IDI2,HMGCS1,FDPS,ZMPSTE24,PMVK,GGPS1,HMGCS2,PCYOX1,ACAT1 |
Protein Function
IDI1 has several biochemical functions, for example, hydrolase activity,isopentenyl-diphosphate delta-isomerase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by IDI1 itself. We selected most functions IDI1 had, and list some proteins which have the same functions with IDI1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| hydrolase activity | CAPN12,PM20D2,TMPRSS7,PLAUB,EAR2,PTPN2B,OVCH2,GPN3,ADPRM,ANG3 |
| isopentenyl-diphosphate delta-isomerase activity | IDI2 |
Interacting Protein
IDI1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IDI1 here. Most of them are supplied by our site. Hope this information will be useful for your research of IDI1.
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