HYAL4
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Official Full Name
hyaluronoglucosaminidase 4 -
Overview
This gene encodes a protein which is similar in structure to hyaluronidases. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is thought to be involved in cell proliferation, migration and differentiation. However, this protein has not yet been shown to have hyaluronidase activity. -
Synonyms
HYAL4;hyaluronoglucosaminidase 4;hyaluronidase-4;hyaluronidase 4;chondroitin sulfate hydrolase;CSHY;Hyal-4;HYAL4_HUMAN;Hyaluronoglucosaminidase-4
Recombinant Proteins
- Human
- Mouse
- E.coli
- CHO
- Mammalian Cell
- HEK293
- Wheat Germ
- GST
- His
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| HYAL4-14021H | Recombinant Human HYAL4, GST-tagged | E.coli | Human | GST | 29-460a.a. | |
| HYAL4-795H | Recombinant Human HYAL4 protein, His-tagged | E.coli | Human | His | 29-460 aa | |
| HYAL4-1973H |
Active Recombinant Human Hyaluronoglucosaminidase 4, His-tagged
|
CHO | Human | His | 34-462 a.a. |
|
| HYAL4-7955M | Recombinant Mouse HYAL4 Protein | Mammalian Cell | Mouse | His |
|
|
| HYAL4-4391M | Recombinant Mouse HYAL4 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
|
|
| HYAL4-4391M-B | Recombinant Mouse HYAL4 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
|
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| HYAL4-5218H | Recombinant Human HYAL4 Protein, GST-tagged | Wheat Germ | Human | GST |
|
Involved Pathway
HYAL4 involved in several pathways and played different roles in them. We selected most pathways HYAL4 participated on our site, such as Glycosaminoglycan degradation,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with HYAL4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolic pathways | ALG1,SDHC,GMPPAB,B3GNT5B,CBR2,CYP2C54,TYRP1B,UGT1A7,FBP1A,FTCD |
| Glycosaminoglycan degradation | HEXB,SPAM1,GNSA,HYAL2,HGSNAT,GNSB,IDUA,GUSB,SGSH,NAGLU |
Protein Function
HYAL4 has several biochemical functions, for example, hyalurononglucosaminidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by HYAL4 itself. We selected most functions HYAL4 had, and list some proteins which have the same functions with HYAL4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| hyalurononglucosaminidase activity | HYAL6,HYAL3,HYAL1,SPAM1,KIAA1199,CD44,MGEA5,HYAL2 |
Interacting Protein
HYAL4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HYAL4 here. Most of them are supplied by our site. Hope this information will be useful for your research of HYAL4.
Resources
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References
- Rizzardi, AE; Vogel, RI; et al. Elevated Hyaluronan and Hyaluronan-Mediated Motility Receptor Are Associated With Biochemical Failure in Patients With Intermediate-Grade Prostate Tumors. CANCER 120:1800-1809(2014).
- Shields, J; Lokeshwar, S; et al. HYAL4: A NEW HYALURONIDASE ASSOCIATED WITH BLADDER CANCER DIAGNOSIS AND PROGNOSIS. JOURNAL OF UROLOGY 191:E301-E302(2014).
