HMGCS1
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Official Full Name
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
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Synonyms
HMGCS1; 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble); 3 hydroxy 3 methylglutaryl Coenzyme A synthase 1 (soluble) , HMGCS; hydroxymethylglutaryl-CoA synthase, cytoplasmic; 3 hydroxy 3 methylglutaryl coenzyme A (HMG CoA) synthase; cytoplasmic; 3 hydroxy 3 methylglutaryl Coenzyme A synthase 1 (soluble); 3-hydroxy-3-methylglutaryl coenzyme A synthase; EC 2.3.3.10; HMCS1_HUMAN; HMG CoA synthase; HMG-CoA synthase; HMGCS; Hydroxymethylglutaryl CoA synthase, cytoplasmic; Hydroxymethylglutaryl-CoA synthase; MGC90332; 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) synthase; 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble);
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Rat
- Rhesus Macaque
- Zebrafish
- E.coli
- HEK293
- HEK293T
- Mammalian Cell
- Wheat Germ
- Yeast
- GST
- His
- Fc
- Avi
- SUMO
- T7
- Myc
- DDK
- Non
- Involved Pathway
- Protein Function
- Interacting Protein
- Other Resource
HMGCS1 involved in several pathways and played different roles in them. We selected most pathways HMGCS1 participated on our site, such as Synthesis and degradation of ketone bodies, Valine, leucine and isoleucine degradation, Butanoate metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with HMGCS1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Synthesis and degradation of ketone bodies | ACAT2;HMGCL;BDH1;HMGCS1;HMGCS2;OXCT1B;OXCT2;ACAT1;OXCT2A |
| Valine, leucine and isoleucine degradation | OXCT1A;ALDH9A1;ACADSB;ALDH2.1;OXCT2;ACAA1;ACAD8;AOX3L1;ACSF3 |
| Butanoate metabolism | HADHAA;GAD1B;ACSM2;DHRS13L1;ACAT2;ACSM1;HMGCS2;ACSM2B;OXCT1A |
| Terpenoid backbone biosynthesis | MVD;PMVK;FDPS;ACAT2;PCYOX1;IDI2;HMGCS1;HMGCS2;FNTB |
| Metabolic pathways | SDSL;PEMT;MUT;ATP6V0A4;AGLA;GPI;UGT1A4;TH;GPT2L |
HMGCS1 has several biochemical functions, for example, drug binding, hydroxymethylglutaryl-CoA synthase activity, isomerase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by HMGCS1 itself. We selected most functions HMGCS1 had, and list some proteins which have the same functions with HMGCS1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| drug binding | IL2RA;GLRB;PPARA;PDE4C;FOLR2;DRD1A;PPARD;MT2A;DHODH |
| hydroxymethylglutaryl-CoA synthase activity | HMGCS2;HMGCS1 |
| isomerase activity | HSD3B6;PGAM1A;FKBP1AB;PGAM1;GPIB;PPIAA;PBLD1;PBLD;DSEL |
| organic acid binding | HBA-A2;HMGCS1 |
| protein homodimerization activity | HRSP12;SLC22A1;CADM1;MYPOP;CD200;NPPC;UGT1A6B;DST;TMEM173 |
HMGCS1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HMGCS1 here. Most of them are supplied by our site. Hope this information will be useful for your research of HMGCS1.
IKBKE; sdhA; nrdD; polg_hcvjf_rna
Research Area
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