HINT2
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Official Full Name
histidine triad nucleotide binding protein 2 -
Overview
Histidine triad proteins, such as HINT2, are nucleotide hydrolases and transferases that act on the alpha-phosphate of;ribonucleotides (Brenner, 2002 (PubMed 12119013)). -
Synonyms
HINT2;histidine triad nucleotide binding protein 2;histidine triad nucleotide-binding protein 2, mitochondrial;HINT-2;HINT-3;HIT-17kDa;PKCI-1-related HIT protein;protein kinase C inhibitor-2;HIT-17
Recombinant Proteins
- Rhesus macaque
- Human
- Zebrafish
- Mouse
- Mammalian Cell
- HEK293
- Wheat Germ
- E.coli
- HEK293T
- In Vitro Cell Free System
- His
- Myc&DDK
- GST
- Non
- His&T7
- His&Fc&Avi
Involved Pathway
HINT2 involved in several pathways and played different roles in them. We selected most pathways HINT2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with HINT2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
HINT2 has several biochemical functions, for example, NOT 1-aminocyclopropane-1-carboxylate synthase activity,protein binding,protein homodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by HINT2 itself. We selected most functions HINT2 had, and list some proteins which have the same functions with HINT2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein homodimerization activity | ATIC,SPPL2B,GPD1A,ABP1,HMGCR,PVRL1,RAB11FIP4,NACC2,CUL3,PRKG2 |
| protein binding | KIR2DL4,ZNF193,Itga10&Itgb1,CRABP2,COX6B2,PRPF40A,MID1,PPP1R3C,SHMT1,C14orf159 |
| pyridoxal phosphate binding | GOT2B,CBSB,PYGL,SRR,SPTLC2,ALAS2,GOT1,CCBL1,SDS,Alb |
| NOT 1-aminocyclopropane-1-carboxylate synthase activity | ACCS |
Interacting Protein
HINT2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HINT2 here. Most of them are supplied by our site. Hope this information will be useful for your research of HINT2.
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References
- Zimon, M; Battaloglu, E; et al. Unraveling the genetic landscape of autosomal recessive Charcot-Marie-Tooth neuropathies using a homozygosity mapping approach. NEUROGENETICS 16:33-42(2015).
- Kumar, SM; Pampa, KJ; et al. Crystal structures of type IIIH NAD-dependent D-3-phosphoglycerate dehydrogenase from two thermophiles. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 451:126-130(2014).
