GTF2I

  • Official Full Name

    general transcription factor IIi

  • Overview

    GTF2l is required for the formation of functional ARID3A DNA-binding complexes and for activation of immunoglobulin heavy-chain transcription upon B-lymphocyte activation.

  • Synonyms

    GTF2I;general transcription factor IIi;general transcription factor II, i , WBSCR6;general transcription factor II-I;BAP 135;BTKAP1;DIWS;IB291;SPIN;TFII I;BTK-associated protein 135;BTK-associated protein, 135kD;SRF-Phox1-interacting protein;Williams-Beuren syndrome chromosome region 6;Bruton tyrosine kinase-associated protein 135;williams-Beuren syndrome chromosomal region 6 protein;WBS;BAP135;TFII-I;WBSCR6;GTFII-I;FLJ38776;FLJ56355

Recombinant Proteins

  • Human
  • Rhesus macaque
  • Rat
  • Mouse
  • E.coli
  • Mammalian Cells
  • Wheat Germ
  • HEK293
  • In Vitro Cell Free System
  • GST
  • His
  • Non
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
GTF2I-13601H Recombinant Human GTF2I, GST-tagged E.coli Human GST 1-274
GTF2I-2010R Recombinant Rhesus monkey GTF2I Protein, His-tagged Mammalian Cells Rhesus macaque His
GTF2I-2745R Recombinant Rat GTF2I Protein Mammalian Cells Rat His
GTF2I-29513TH Recombinant Human GTF2I Wheat Germ Human Non 239 amino acids
GTF2I-29514TH Recombinant Human GTF2I Wheat Germ Human Non 274 amino acids
GTF2I-4454H Recombinant Human GTF2I Protein, GST-tagged Wheat Germ Human GST
GTF2I-7363M Recombinant Mouse GTF2I Protein Mammalian Cells Mouse His
GTF2I-763HCL Recombinant Human GTF2I cell lysate Human Non
GTF2I-15H Recombinant Human GTF2I Protein (1-976), N-GST-tagged Wheat Germ Human GST 1-976
GTF2I-1831R Recombinant Rhesus Macaque GTF2I Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque His&Fc&Avi
GTF2I-1831R-B Recombinant Rhesus Macaque GTF2I Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
GTF2I-214HF Recombinant Full Length Human GTF2I Protein In Vitro Cell Free System Human Full L. 274 amino acids
GTF2I-2399R Recombinant Rat GTF2I Protein, His (Fc)-Avi-tagged HEK293 Rat His&Fc&Avi
GTF2I-2399R-B Recombinant Rat GTF2I Protein Pre-coupled Magnetic Beads HEK293 Rat
GTF2I-3399HF Recombinant Full Length Human GTF2I Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 274 amino acids
GTF2I-3993M Recombinant Mouse GTF2I Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
GTF2I-3993M-B Recombinant Mouse GTF2I Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    GTF2I involved in several pathways and played different roles in them. We selected most pathways GTF2I participated on our site, such as Basal transcription factors,cGMP-PKG signaling pathway,Herpes simplex infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with GTF2I were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Herpes simplex infection SRSF4,EIF2AK3,FAS,CLOCKB,IFNG,IFNAR1,TNFB,Fasl,SRSF7A,HCFC1B
    cGMP-PKG signaling pathway BDKRB2,PLCB2,AKT2,ATF4,PIK3CB,PLCB4,SLC25A5,PLCB1,ATP1B4,VDAC2
    Basal transcription factors TAF6L,TAF1L,TAF5L,TAF4B,GTF2A2,TAF8,GTF2H3,TAF7L,TAF7,MNAT1

    Protein Function

    GTF2I has several biochemical functions, for example, DNA binding,mitogen-activated protein kinase binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GTF2I itself. We selected most functions GTF2I had, and list some proteins which have the same functions with GTF2I. You can find most of the proteins on our site.

    Function Related Protein
    transcription factor activity, sequence-specific DNA binding SMAD2,TSC22D3,FBXW7,ZNF501,HOXB2A,NPAS2,BSX,HES6,MEF2B,ZBTB48
    protein binding NHLRC1,GPRASP1,NEUROG3,EIF1AD,PHF19,PER3,FRK,CLK3,FOXJ2,RAD17
    mitogen-activated protein kinase binding MAPKAPK2B,MAPKAPK5,PLCB4,MAPKAPK2,PTPRJ,DUSP2,EP300,TNIP1,MAPK7,MAPKAPK2A
    DNA binding RBM6,ZFAT,PLAGL1,THAP7,H1M,CERS2A,ZNF69,ZNF496,KLF12,NR2F6A

    Interacting Protein

    GTF2I has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GTF2I here. Most of them are supplied by our site. Hope this information will be useful for your research of GTF2I.

    BTK;BRCA1;PTP4A3;Btk;NR4A2;MAGEA6;ARF6;NFKB2;USP7;OTUB2;GSTK1

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