GSTM1
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Official Full Name
glutathione S-transferase mu 1 -
Overview
GST Yb1 is a sensitive biomarker located in the liver and in kidney tubules. GST Yb1 has been shown to be useful in renal studies. -
Synonyms
GSTA3;GST 3-3;GST Yb1;GSTM1-1;glutathione S-transferase M1;glutathione S-transferase Mu 1;glutathione S-transferase Yb-1 subunit;glutathione-S-transferase mu type 1 (Yb1);glutathione-S-transferase, mu type 1 (Yb1)
Recombinant Proteins
- Mouse
- Human
- Rat
- Mouse
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- Yeast
- E. coli
- Non
- His
- GST
- His&Fc&Avi
- N-His-sumostar
- His&SUMO
Involved Pathway
GSTM1 involved in several pathways and played different roles in them. We selected most pathways GSTM1 participated on our site, such as Glutathione metabolism,Metabolism of xenobiotics by cytochrome P,Drug metabolism - cytochrome P, which may be useful for your reference. Also, other proteins which involved in the same pathway with GSTM1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Chemical carcinogenesis | CYP2E1,ADH1A,MGST2,CYP3A5,UGT1A7C,GSTO2,CYP2B19,CYP2C9,CYP2C19,ARNT |
| Metabolism of xenobiotics by cytochrome P | GSTM3,AKR7A2,CBR1L,GSTM4,GSTM7,UGT2A1,MGST1.1,HSD11B1,GSTM6,CBR2 |
| Glutathione metabolism | RRM2,GGT7,GCLC,GSTAL,MGST1.1,G6PD,GGT6,GSTA5,GSTA3,GPX7 |
| Drug metabolism - cytochrome P | ALDH3A1,MAOB,UGT2B15,AOX2P,UGT1A6B,UGT1A1,GSTM,MAOA,UGT1A7C,AOX3 |
Protein Function
GSTM1 has several biochemical functions, for example, enzyme binding,glutathione binding,glutathione transferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GSTM1 itself. We selected most functions GSTM1 had, and list some proteins which have the same functions with GSTM1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein homodimerization activity | DPY30,AADAT,CALCOCO2,SRR,ATPIF1A,STK10,FZD9,USH2A,RAB11FIP4B,KIAA0947 |
| enzyme binding | BCHE,GSTM3,RPS19BP1,PEX5,APOA5,NOS1,U2AF2,AKIRIN2,UGT1A6B,PPP1R3B |
| glutathione transferase activity | GSTA1,GSTT2B,GSTM7,GSTA3,GRX2,GSTAL,GSTM4,LTC4S,GSTM,GSTM3 |
| glutathione binding | GSTM7,PTGES2,GSTP2,GSTM3,PTGES,GSTM4,GSTM2,GSS,GPX1,MGST1 |
Interacting Protein
GSTM1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GSTM1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GSTM1.
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References
- Polosukhin, VV; Polosukhin, IV; et al. Glutathione S-transferase M1 modulates allergen-induced NF-kappa B activation in asthmatic airway epithelium. ALLERGY 69:1666-1672(2014).
- Rupasree, Y; Naushad, SM; et al. Association of genetic variants of xenobiotic metabolic pathway with systemic lupus erythematosus. INDIAN JOURNAL OF BIOCHEMISTRY & BIOPHYSICS 50:447-452(2013).
