GPER
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Official Full Name
G protein-coupled estrogen receptor 1 -
Overview
This gene is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum. The protein binds estrogen, resulting in intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. Alternate transcriptional splice variants which encode the same protein have been characterized. -
Synonyms
GPER;G protein-coupled estrogen receptor 1;CMKRL2, G protein coupled receptor 30 , GPR30;G-protein coupled estrogen receptor 1;CEPR;DRY12;FEG 1;GPCR Br;LERGU;LERGU2;LyGPR;mER;heptahelix receptor;chemokine receptor-like 2;IL8-related recepto
Recombinant Proteins
- Rat
- Human
- Mammalian Cell
- E.coli
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- His
- His&GST
- His&Fc&Avi
- Non
- GST
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| GPER-2637R | Recombinant Rat GPER Protein | Mammalian Cell | Rat | His |
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| GPER-1580H | Recombinant Human GPER Protein, His&GST-tagged | E.coli | Human | His&GST | Met1-Ser62 |
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| GPER-2291R | Recombinant Rat GPER Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| GPER-2291R-B | Recombinant Rat GPER Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| GPER-5154H | Recombinant Human GPER Protein | Wheat Germ | Human | Non |
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| GPER-5230H | Recombinant Human GPER Protein, GST-tagged | Wheat Germ | Human | GST |
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| GPER-5528HF | Recombinant Full Length Human GPER Protein | In Vitro Cell Free System | Human | Full L. 396 amino acids |
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| GPER-5532HF | Recombinant Full Length Human GPER Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 375 amino acids |
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Involved Pathway
GPER involved in several pathways and played different roles in them. We selected most pathways GPER participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with GPER were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
GPER has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by GPER itself. We selected most functions GPER had, and list some proteins which have the same functions with GPER. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
GPER has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GPER here. Most of them are supplied by our site. Hope this information will be useful for your research of GPER.
Resources
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References
- Chourasia, TK; Pang, YF; et al. The Catecholestrogen, 2-Hydroxyestradiol-17beta, Acts as a G Protein-Coupled Estrogen Receptor 1 (GPER/GPR30) Antagonist to Promote the Resumption of Meiosis in Zebrafish Oocytes. BIOLOGY OF REPRODUCTION 92:-(2015).
- Li, YR; Ren, CE; et al. Expression of G protein estrogen receptor (GPER) on membrane of mouse oocytes during maturation. JOURNAL OF ASSISTED REPRODUCTION AND GENETICS 30:227-232(2013).
