Gpc2
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Official Full Name
glypican 2 (cerebroglycan) -
Synonyms
GPC2;glypican 2 (cerebroglycan);cerebroglycan;DKFZp547M109;FLJ38962;glypican proteoglycan 2;cerebroglycan proteoglycan;Q8N158
Recombinant Proteins
- Human
- Mouse
- Rat
- Zebrafish
- Rhesus macaque
- Mammalian cells
- HEK293
- Mammalian Cell
- E.coli
- His
- C-LFc
- Fc
- His&Fc&Avi
Involved Pathway
Gpc2 involved in several pathways and played different roles in them. We selected most pathways Gpc2 participated on our site, such as A tetrasaccharide linker sequence is required for GAG synthesis,Chondroitin sulfate/dermatan sulfate metabolism,Glycosaminoglycan metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with Gpc2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| A tetrasaccharide linker sequence is required for GAG synthesis | GPC1B,DCN,BGNB,B4GALT7,AGRN,VCANB,BCAN,NCAN,VCAN,BGNA |
| Metabolism | SLC19A2,KIAA1199,APOC2,CEPT1A,BCHE,CDS1,SURF1,ACOT10,FAAH2A,NFYBA |
| Glycosaminoglycan metabolism | CHST9,KIAA1199,CHST14,VCANB,OGN,SLC35B3,FMODA,HS3ST6,BGNB,HAS3 |
| HS-GAG degradation | GPC1B,GLB1L,GPC1A,GPC5A,HPSE |
| Metabolism of carbohydrates | CHST9,GLB1L,GCKR,KHK,SLC5A2,TREH,B3GNT3,SLC5A4,CHST14,DSEL |
| Heparan sulfate/heparin (HS-GAG) metabolism | HS3ST6,HS3ST4,SLC35D2,GLB1L,B4GALT7,CSPG5B,GPC1A,GPC1B,HPSE,MAPK1IP1L |
| HS-GAG biosynthesis | HS3ST4,GPC1B,SLC35D2,GPC5A,MAPK1IP1L,HS3ST6,GPC1A |
| Chondroitin sulfate/dermatan sulfate metabolism | GPC5A,CSPG5,GPC6,DSEL,BGN,BGNB,GPC5,GPC1B,GPC1A,DCN |
Protein Function
Gpc2 has several biochemical functions, for example, heparan sulfate proteoglycan binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Gpc2 itself. We selected most functions Gpc2 had, and list some proteins which have the same functions with Gpc2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| heparan sulfate proteoglycan binding | COMP,CFH,GPC1B,AGRN,GPC4,UBE4A,GPC1A,GPC3,SEMA5A,GPC1 |
Interacting Protein
Gpc2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Gpc2 here. Most of them are supplied by our site. Hope this information will be useful for your research of Gpc2.
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References
- Wang, XM; Liu, JH; et al. The heparan sulfate-modifying enzyme glucuronyl C5-epimerase HSE-5 controls Caenorhabditis elegans Q neuroblast polarization during migration. DEVELOPMENTAL BIOLOGY 399:306-314(2015).
- Weissferdt, A; Rodriguez-Canales, J; et al. Primary mediastinal seminomas: a comprehensive immunohistochemical study with a focus on novel markers. HUMAN PATHOLOGY 46:376-383(2015).
