GNG2
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Official Full Name
Guanine Nucleotide Binding Protein (G Protein), Gamma 2 -
Overview
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 is a protein that in humans is encoded by the GNG2 gene. -
Synonyms
GNG2;G gamma-I;guanine nucleotide binding protein (G protein), gamma 2;guanine nucleotide binding protein gamma 2;guanine nucleotide-binding protein G(I)/G(O) gamma-2 subunit;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2;Gγ-2-Subunit;G gamma I;GNG 2
Recombinant Proteins
- Human
- Rhesus macaque
- Chicken
- Zebrafish
- Mouse
- E.coli
- Mammalian Cells
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- GST
- His
- Non
- DDK
- Myc
- Avi
- Fc
Involved Pathway
GNG2 involved in several pathways and played different roles in them. We selected most pathways GNG2 participated on our site, such as Ras signaling pathway,Chemokine signaling pathway,PIK-Akt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with GNG2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Pathways in cancer | WNT8B,ROCK1,TGFBR1,KITLG,BIRC3,WNT6,STAT5A,HSP90B1,NFKBIA,GNAQ |
| Glutamatergic synapse | GNB2,ITPR3,PPP3CC,MAPK3,GRIN3B,GNAI2,SLC17A6,GRIK5,GNAI1,SLC17A7 |
| Cholinergic synapse | FYN,KCNJ3,KCNQ3,Adcy4,PIK3R3,JAK2,CAMK4,CREB3L4,CREB3,GNB3 |
| Retrograde endocannabinoid signaling | PTGS2,GNAI2,GABRG2,GRIA1,PRKCA,GNAI3,Adcy4,GABRG3,GNB2,MAPK12 |
| Ras signaling pathway | PDGFD,PIK3R2,GNG13,RAC1,PLA2G2F,PIK3R5,HTR7,PLA2G10,ZAP70,FGF22 |
| Alcoholism | GM14477,MAP2K1,HIST3H2BB,H2AFJ,CREB3,GRIN2D,CREB5,SHC3,HAT1,H2AFX |
| Dopaminergic synapse | GNB2,PPP2R5A,COMT,PPP2R3A,KIF5C,GRIN2A,CREB3,SLC6A3,DRD1A,KIF5A |
| GABAergic synapse | GAD1,GABRA3,GNG12,GABRP,SLC38A3,GNAO1,SLC38A5,SLC12A5,GNAI3,GNG5 |
| PIK-Akt signaling pathway | PPP2R5C,FGF17,IFNA1,IRS1,Il6ra,ITGA8,RXRA,GNB3,FGF13,PKN1 |
Protein Function
GNG2 has several biochemical functions, for example, G-protein beta-subunit binding,signal transducer activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GNG2 itself. We selected most functions GNG2 had, and list some proteins which have the same functions with GNG2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| signal transducer activity | PKP1,GNG5,LPAR6A,OLFR13,VOPP1,GNAZ,STAT5A,GNG13A,S1PR5A,MUL1 |
| G-protein beta-subunit binding | OPRM1,F2RL1,GNG13,CCT5,RGS7,RGS9,RASD2,RGS11,F2R |
Interacting Protein
GNG2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GNG2 here. Most of them are supplied by our site. Hope this information will be useful for your research of GNG2.
GNAI1;Fnta
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