EXOC7
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Official Full Name
exocyst complex component 7 -
Overview
The protein encoded by this gene is a component of the exocyst complex. The exocyst complex plays a critical role in vesicular trafficking and the secretory pathway by targeting post-Golgi vesicles to the plasma membrane. The encoded protein is required for assembly of the exocyst complex and docking of the complex to the plasma membrane. The encoded protein may also play a role in pre-mRNA splicing through interactions with pre-mRNA-processing factor 19.Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 4. -
Synonyms
EXOC7;exocyst complex component 7;EXO70;Exo70p;KIAA1067;YJL085W;exocyst complex component Exo70;EX070;EXOC1;2-5-3p;FLJ40965;FLJ46415;DKFZp686J04253
Recombinant Proteins
- Zebrafish
- Chicken
- Rat
- Human
- Mouse
- Mammalian Cell
- E.coli
- Wheat Germ
- HEK293
- HEK293T
- Mamanlian cells
- His
- GST
- Myc&DDK
- Non
- His&Fc&Avi
- Flag
Involved Pathway
EXOC7 involved in several pathways and played different roles in them. We selected most pathways EXOC7 participated on our site, such as Insulin signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with EXOC7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Insulin signaling pathway | PRKAR1A,PRKACBA,PHKG1B,GRB2A,RPS6KB1,CALM1,FLOT1A,TSC1A,PIK3R1,TRIP10 |
Protein Function
EXOC7 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EXOC7 itself. We selected most functions EXOC7 had, and list some proteins which have the same functions with EXOC7. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | CLK4,SPC24,EFNB2,TMEM41A,TOP2A,HDLBP,SLC25A6,EIF4B,RWDD1,HMGA1 |
Interacting Protein
EXOC7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EXOC7 here. Most of them are supplied by our site. Hope this information will be useful for your research of EXOC7.
HGS;IFT20;SSC5D;SMARCE1;EGFR;LAPTM4B
Resources
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References
- Lee, MS; Lin, YS; et al. Modulation of alternative splicing by expression of small nuclear ribonucleoprotein polypeptide N. FEBS JOURNAL 281:5194-5207(2014).
- Evers, C; Maas, B; et al. Mosaic Deletion of EXOC6B: Further Evidence for An Important Role of the Exocyst Complex in the Pathogenesis of Intellectual Disability. AMERICAN JOURNAL OF MEDICAL GENETICS PART A 164A:3088-3094(2014).
