ETV1
-
Official Full Name
ets variant 1 -
Overview
This gene encodes a member of the ETS (E twenty-six) family of transcription factors. The ETS proteins regulate many target genes that modulate biological processes like cell growth, angiogenesis, migration, proliferation and differentiation. All ETS proteins contain an ETS DNA-binding domain that binds to DNA sequences containing the consensus 5-CGGA -
Synonyms
ETV1;ets variant 1;ets variant gene 1;ETS translocation variant 1;ER81;MGC104699;MGC120533;MGC120534;DKFZp781L0674;ER81 protein;Ets-related protein 81;Etsrp81;ETV 1;ETV1_HUMAN;OTTHUMP00000201615;OTTHUMP00000201616;OTTHUMP00000201617;OTTHUMP00000201618;OTTHUMP00000201619;OTTHUMP00000201620;OTTHUMP00000201621;OTTHUMP00000201622
Recombinant Proteins
- Human
- Zebrafish
- Cynomolgus
- Chicken
- Mouse
- Wheat Germ
- Mammalian Cell
- HEK293
- E. coli
- Mammalian cells
- HEK293T
- In Vitro Cell Free System
- Non
- His
- GST
- N-His
- N-GST
- Flag
- His&Fc&Avi
- Myc&DDK
Involved Pathway
ETV1 involved in several pathways and played different roles in them. We selected most pathways ETV1 participated on our site, such as Transcriptional misregulation in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with ETV1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Transcriptional misregulation in cancer | TP53,PAX7,ETV4,SP1,IL1R2,MEF2C,HIST3H3,HIST2H3C1,FOXO1,ETV7 |
Protein Function
ETV1 has several biochemical functions, for example, RNA polymerase II core promoter proximal region sequence-specific DNA binding,protein binding,transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ETV1 itself. We selected most functions ETV1 had, and list some proteins which have the same functions with ETV1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transcription factor activity, sequence-specific DNA binding | TCF19,DBPB,FOXC1B,ATF4B2,ZNF234,WT1,SPI1A,SUPT4H1,ZSCAN16,NFIL3-6 |
| protein binding | DIAPH1,CXXC5,ORMDL3,MTERF,INTS7,POC1B,SPPL3,KRR1,SGCG,THOC4 |
| transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding | CEBPA,NCOA3,PITX2,SPI1,BARHL2,MEIS3,HLTF,MAFB,TRP53,TRP63 |
| RNA polymerase II core promoter proximal region sequence-specific DNA binding | RUNX2,ZNF114,NRF1,AEBP2,EBF2,CLOCK,NACC2,PGR,OTX1,HELT |
Interacting Protein
ETV1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ETV1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ETV1.
psen1_human_dna_probe;PRKDC;CCND3;PARP1;XRCC6;XRCC5;RFWD2
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