ESCO1
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Official Full Name
establishment of cohesion 1 homolog 1 (S. cerevisiae) -
Overview
ESCO1 belongs to a conserved family of acetyltransferases involved in sister chromatid cohesion (Hou and Zou, 2005;(PubMed 15958495)). -
Synonyms
ESCO1;establishment of cohesion 1 homolog 1 (S. cerevisiae);N-acetyltransferase ESCO1;EFO1;ESO1;KIAA1911;EFO1p;hEFO1;CTF7 homolog 1;ECO1 homolog 1;ESO1 homolog 1;establishment factor-like protein 1;CTF;ECO1;A930014I12Rik
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ESCO1-3496H | Recombinant Human ESCO1 Protein, GST-tagged | Wheat Germ | Human | GST |
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| ESCO1-5318M | Recombinant Mouse ESCO1 Protein | Mammalian Cells | Mouse | His |
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| ESCO1-572HCL | Recombinant Human ESCO1 cell lysate | Human | Non |
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| ESCO1-2861M | Recombinant Mouse ESCO1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| ESCO1-2861M-B | Recombinant Mouse ESCO1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| ESCO1-4698HF | Recombinant Full Length Human ESCO1 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 172 amino acids |
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Involved Pathway
ESCO1 involved in several pathways and played different roles in them. We selected most pathways ESCO1 participated on our site, such as Cell Cycle,Cell Cycle, Mitotic,Establishment of Sister Chromatid Cohesion, which may be useful for your reference. Also, other proteins which involved in the same pathway with ESCO1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cell cycle | CCP110,ACD,BARD1,NDE1,CCNH,NDEL1A,TMPO,RBL2,TGFB1A,PLK4 |
| Establishment of Sister Chromatid Cohesion | STAG2,STAG1,PDS5B,WAPAL,ESCO2,CDCA5,PDS5A |
| Cell Cycle, Mitotic | CETN2,SSNA1,CENPE,TMEM188,MCM8,HIST4H4,GOLGA2,FGFR1OP,NCAPG,NSL1 |
| S Phase | MYCA,GINS4,ESCO2,GINS3,GINS1,GINS2 |
Protein Function
ESCO1 has several biochemical functions, for example, metal ion binding,transferase activity, transferring acyl groups. Some of the functions are cooperated with other proteins, some of the functions could acted by ESCO1 itself. We selected most functions ESCO1 had, and list some proteins which have the same functions with ESCO1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transferase activity, transferring acyl groups | MEIS2,ACAA1A,SPTLC3,CHATA,GGACT.1,LPCAT3,EP300,LYCAT,ZDHHC15B,GGACT.3 |
| metal ion binding | NAALAD2,ENDOG,ZNF554,ZNF486,PDE10A,YOD1,IKZF4,ESYT1,CIT,CBS |
Interacting Protein
ESCO1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ESCO1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ESCO1.
Esco1
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References
- Carretero, M; Ruiz-Torres, M; et al. Pds5B is required for cohesion establishment and Aurora B accumulation at centromeres. EMBO JOURNAL 32:2938-2949(2013).
- Price, JC; Pollock, LM; et al. Sequencing of Candidate Chromosome Instability Genes in Endometrial Cancers Cancers Reveals Somatic Mutations in ESCO1, CHTF18, and MRE11A. PLOS ONE 8:-(2013).
