ENTPD2
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Official Full Name
ectonucleoside triphosphate diphosphohydrolase 2 -
Overview
The protein encoded by this gene is the type 2 enzyme of the ecto-nucleoside triphosphate diphosphohydrolase family (E-NTPDase). E-NTPDases are a family of ecto-nucleosidases that hydrolyze 5-triphosphates. This ecto-ATPase is an integral membrane protein. Alternative splicing of this gene results in multiple transcript variants. -
Synonyms
ENTPD2;ectonucleoside triphosphate diphosphohydrolase 2;CD39L1;CD39 like 1;ecto ATPase;NTPDase 2;ecto-ATPase 2;ecto-ATPDase 2;CD39 antigen-like 1;ecto-ATP diphosphohydrolase 2;NTPDase-2
Recombinant Proteins
- Human
- Mouse
- Rat
- Chicken
- Mus musculus
- Insect Cells
- CHO
- HEK293
- Mammalian Cells
- Wheat Germ
- E.coli
- His
- Non
- GST
- His&Fc&Avi
Involved Pathway
ENTPD2 involved in several pathways and played different roles in them. We selected most pathways ENTPD2 participated on our site, such as Purine metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with ENTPD2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Purine metabolism | PDE6B,GDA,POLE4,PNP6,PKM2,AK7,POLR1E,NME7,NME2A,PDE11A |
Protein Function
ENTPD2 has several biochemical functions, for example, ATP binding,ATPase activity,adenosine-diphosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ENTPD2 itself. We selected most functions ENTPD2 had, and list some proteins which have the same functions with ENTPD2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| identical protein binding | PLDN,ROBO1,NONO,CUBN,RUVBL2,CEP170L,DYNLT1A,CLDN4,ACTG1,SMAD6 |
| ATPase activity | TOR1B,MLH1,OLA1,ABCA13,CENPE,ABCE1,ABCF1,ABCF2A,MACF1,ABCG4B |
| ATP binding | NAV3,CSF1R,CAMK2B1,MCCC1,EEF2K,HSPA12A,FLT4,RET,CHORDC1,KIF25 |
| adenosine-diphosphatase activity | NUDT9,SLC25A42 |
Interacting Protein
ENTPD2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ENTPD2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ENTPD2.
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References
- Vekaria, RM; Shirley, DG; et al. Immunolocalization of ectonucleotidases along the rat nephron. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY 290:F550-F560(2006).
