DKK2
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Official Full Name
dickkopf 2 homolog -
Overview
Dickkopf (DKK) family proteins consist of four members DKK1, DKK2, DKK3 and DKK4 that function as secreted Wnt antagonists by inhibiting Wnt coreceptors LRP5 and LRP6. DKKs contain two cysteine-rich domains in which the positions of 10 cysteine residues a -
Synonyms
DKK2;dickkopf 2 homolog (Xenopus laevis);dickkopf (Xenopus laevis) homolog 2;dickkopf-related protein 2;hDkk-2;dickkopf-2;dickkopf homolog 2;dickkopf related protein-2;DKK-2
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- E.coli
- Mammalian Cells
- Insect Cells
- S.frugiperda
- CHO
- Wheat Germ
- HEK293
- Yeast
- In Vitro Cell Free System
- His
- Fc
- Non
- GST
- Avi
- SUMO
Involved Pathway
DKK2 involved in several pathways and played different roles in them. We selected most pathways DKK2 participated on our site, such as Wnt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with DKK2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Wnt signaling pathway | PPARDB,DKK1B,SIAH1,PRKACA,PRICKLE1A,PPP3R1B,FBXW11A,NFATC3,WNT11,PPP3R1 |
Protein Function
DKK2 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by DKK2 itself. We selected most functions DKK2 had, and list some proteins which have the same functions with DKK2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
DKK2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DKK2 here. Most of them are supplied by our site. Hope this information will be useful for your research of DKK2.
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References
- Aravalli, RN; Talbot, NC; et al. Gene expression profiling of MYC-driven tumor signatures in porcine liver stem cells by transcriptome sequencing. WORLD JOURNAL OF GASTROENTEROLOGY 21:2011-2029(2015).
- Hong, FS; Hong, J; et al. Chronic Exposure to Nanoparticulate TiO2 Causes Renal Fibrosis Involving Activation of the Wnt Pathway in Mouse Kidney. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 63:1639-1647(2015).
