CRTC2
-
Official Full Name
CREB regulated transcription coactivator 2 -
Overview
Glucose homeostasis is regulated by hormones and cellular energy status. Elevations of blood glucose during feeding stimulate insulin release from pancreatic beta-cells through a glucose sensing pathway. Feeding also stimulates release of gut hormones suc -
Synonyms
CRTC2;CREB regulated transcription coactivator 2;CREB-regulated transcription coactivator 2;TORC2;transducer of regulated cAMP response element-binding protein (CREB) 2;TORC-2
Recombinant Proteins
- Human
- Rhesus macaque
- E.coli
- Mammalian Cells
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- GST
- His
- Non
- His&GST
- His&Fc&Avi
Involved Pathway
CRTC2 involved in several pathways and played different roles in them. We selected most pathways CRTC2 participated on our site, such as PIK-Akt signaling pathway,AMPK signaling pathway,Insulin resistance, which may be useful for your reference. Also, other proteins which involved in the same pathway with CRTC2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| PIK-Akt signaling pathway | PDGFRA,MTCP1,PRKAA2,IL7R,TCL1A,IRS1,IFNA2,RBL2,CASP9,F2R |
| AMPK signaling pathway | CCND1,ADRa1A,RAB10,CD36,PPP2R5D,CREB3L1,IRS1,PRKAA1,CPT1B,PPP2R3C |
| Insulin resistance | PIK3CB,PIK3R3,PDPK1,PYGM,PPP1CBL,GSK3B,G6PC3,RPS6KAL,PYGMA,SLC2A2 |
| HTLV-I infection | SPI1,WNT9A,TSPO,HLA-DRB5,CREM,ITGB2L,WNT2,WNT3A,IL15RA,VCAM1 |
Protein Function
CRTC2 has several biochemical functions, for example, cAMP response element binding protein binding,chromatin binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CRTC2 itself. We selected most functions CRTC2 had, and list some proteins which have the same functions with CRTC2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| chromatin binding | NEUROD1,REST,TAL1,REL,ZFP354B,ASH1L,EWSR1A,PDX1,MTA3,MEOX1 |
| protein binding | CNIH2,NUDT14,ATF5,UNC119,CCT7,SOS1,AKT1,JMJD6,TBC1D7,PTPRZ1 |
| cAMP response element binding protein binding | KCNA3,ATF2,CRTC1,CREM,CREB3,CRTC3,DDIT3,CRTC1A,DAPK3 |
Interacting Protein
CRTC2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CRTC2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CRTC2.
YWHAB;bzlf1_ebvb9;SIK1;SIK3;YWHAG;CREBBP;Sec24c;MEIS1;CLTC;GTSE1
Resources
Related Services
Related Products
References
