CORO1C
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Official Full Name
coronin, actin binding protein, 1C -
Overview
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. -
Synonyms
CORO1C;coronin, actin binding protein, 1C;coronin-1C;coronin 3;HCRNN4;coronin-3;coronin 1C;coronin, actin-binding protein, 1C
Recombinant Proteins
- Human
- Chicken
- Rhesus macaque
- Mouse
- E.coli
- Wheat Germ
- Mammalian Cell
- HEK293
- Mammalian cells
- In Vitro Cell Free System
- HEK293T
- His
- GST
- Non
- Flag
- Myc&DDK
- His&Fc&Avi
Involved Pathway
CORO1C involved in several pathways and played different roles in them. We selected most pathways CORO1C participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CORO1C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
CORO1C has several biochemical functions, for example, Rac GTPase binding,actin filament binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CORO1C itself. We selected most functions CORO1C had, and list some proteins which have the same functions with CORO1C. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| Rac GTPase binding | PAK4,DOCK4,SRGAP3,PAK3,PAK6,MAP3K11,NOX1,RCC2,FMNL1,PAK2 |
| actin filament binding | MYH3,CORO1A,SPTA1,MYO7A,ARPC1A,TMOD1,JUB,CTNNAL1,ESPN,MTSS1 |
| protein binding | SEPT11,DLGAP4,PEX13,NDRG4,DCTN2,MAB21L3,GNL3L,IL6R,SYMPK,CPSF7 |
Interacting Protein
CORO1C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CORO1C here. Most of them are supplied by our site. Hope this information will be useful for your research of CORO1C.
VCAM1;Cdk1;Cep76;USP45;Sass6;Poc1b;MAP3K3;RIPK3;LMO2;Cenpe;MYO1C;Flot1;FN1;FLNA;CDK2;MYH9
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References
- Mataki, H; Enokida, H; et al. Downregulation of the microRNA-1/133a cluster enhances cancer cell migration and invasion in lung-squamous cell carcinoma via regulation of Coronin1C. JOURNAL OF HUMAN GENETICS 60:53-61(2015).
- Wang, J; Tsouko, E; et al. miR-206 inhibits cell migration through direct targeting of the actin-binding protein Coronin 1C in triple-negative breast cancer. MOLECULAR ONCOLOGY 8:1690-1702(2014).
