COL13A1

  • Official Full Name

    collagen, type XIII, alpha 1
  • Overview

    This gene encodes the alpha chain of one of the nonfibrillar collagens. The function of this gene product is not known, however, it has been detected at low levels in all connective tissue-producing cells so it may serve a general function in connective tissues. Unlike most of the collagens, which are secreted into the extracellular matrix, collagen XIII contains a transmembrane domain and the protein has been localized to the plasma membrane. The transcripts for this gene undergo complex and extensive splicing involving at least eight exons. Like other collagens, collagen XIII is a trimer; it is not known whether this trimer is composed of one or more than one alpha chain isomer. A number of alternatively spliced transcript variants have been described, but the full length nature of some of them has not been determined.
  • Synonyms

    COL13A1;collagen, type XIII, alpha 1;collagen alpha-1(XIII) chain;CODA1_HUMAN;collagentype XIII alpha 1;collagen alpha 1(XIII) chain;COLXIIIA1
Cat.# Product name Source (Host) Species Tag Protein Length Price
Col13a1-325M Active Recombinant Mouse Col13a1, His-tagged Mammalian Cells Mouse His 107-565 a.a.
Col13a1-465M Active Recombinant Mouse Collagen, Type XIII, Alpha 1, His-tagged Mammalian Cells Mouse His 107-565 a.a.
COL13A1-3717M Recombinant Mouse COL13A1 Protein Mammalian Cells Mouse His
COL13A1-7379HCL Recombinant Human COL13A1 293 Cell Lysate HEK293 Human Non
Col13a1-1846M Recombinant Mouse Col13a1 Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
Col13a1-1846M-B Recombinant Mouse Col13a1 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    COL13A1 involved in several pathways and played different roles in them. We selected most pathways COL13A1 participated on our site, such as Collagen biosynthesis and modifying enzymes,Collagen degradation,Collagen formation, which may be useful for your reference. Also, other proteins which involved in the same pathway with COL13A1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Collagen degradation MMP19,COL19A1,MMP15,COL23A1,MMP13,ADAM10,MMP12,COL15A1B,MMP11,MMP8
    Collagen biosynthesis and modifying enzymes COL9A1A,COL9A3,COL6A3,LEPRE1,EMID2,COL10A1A,TLDC2,BMP1B,SERPINH1,ADAMTS2
    Collagen formation MMP13,LOXL2,COL9A1B,PCOLCEB,COL17A1A,LOXL3,SERPINH1,CD151,COL9A1A,TLDC2
    Integrin cell surface interactions FN1B,F11R.2,BSG,JAM2B,ICAM4,COL9A1B,FBN1,COL16A1,LOC100514666,COL9A1A
    Degradation of the extracellular matrix CTSG,CTSD,CTSB,BMP1A,CTSLL,TLL2,CTSL1,ADAM8A,COL9A3,MMP8
    Extracellular matrix organization COL10A1,TPSAB1,LAMC3,COL6A2,DMP1,SERPINH1B,COL1A1,COL5A3B,TIMP2,CD151
    Protein digestion and absorption PRCP,COL18A1,PRSS1,COL10A1,KCNK5,ACE2,ATP1B4,CTRL,ATP1B3,SLC1A5

    Protein Function

    COL13A1 has several biochemical functions, for example, heparin binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by COL13A1 itself. We selected most functions COL13A1 had, and list some proteins which have the same functions with COL13A1. You can find most of the proteins on our site.

    Function Related Protein
    protein binding TLE3A,IPO11,SLC8A1,LUC7L,RAD51C,ITGB1,ZBED4,ATF4,SIX3,RPS6KA3
    heparin binding PDCD5,LPL,WISP1B,F11,ADAMTSL5,VTN,LTBP2,FSTL1,PF4,SLIT1

    Interacting Protein

    COL13A1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with COL13A1 here. Most of them are supplied by our site. Hope this information will be useful for your research of COL13A1.

    Resources

    References

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