COIL
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Official Full Name
Coilin -
Overview
Coilin is a component of the nuclear Cajar(coiled) bodies (CBs) which are involved in the function or assembly/disassembly of nucleoplasmic snRNPs. Human coilin is a 576-amino acid protein found enriched in CBs, but is also found in large amounts in the nucleoplasm. Coilin is a constitutive phosphoprotein that is hyperphosphorylated during mitosis and it is thought that hyperphosphorylation triggers CB disassembly during cell replication. Self-interaction and localization have been shown to depend on the phosphorylation state of coilin. -
Synonyms
COIL;coilin;p80;coilin p80;CLN80;p80-coilin
Recombinant Proteins
- Human
- Zebrafish
- Rhesus macaque
- Wheat Germ
- E.coli
- Mammalian Cell
- HEK293
- In Vitro Cell Free System
- GST
- Non
- His&T7
- His
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| COIL-1633H | Recombinant Human COIL Protein, GST-tagged | Wheat Germ | Human | GST |
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| COIL-26172TH | Recombinant Human COIL | Wheat Germ | Human | Non | 99 amino acids |
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| COIL-2717H | Recombinant Human COIL protein, His & T7-tagged | E.coli | Human | His&T7 | Ser319~Glu538 |
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| COIL-9061Z | Recombinant Zebrafish COIL | Mammalian Cell | Zebrafish | His |
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| COIL-958R | Recombinant Rhesus monkey COIL Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| COIL-7380HCL | Recombinant Human COIL 293 Cell Lysate | HEK293 | Human | Non |
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| COIL-2086HF | Recombinant Full Length Human COIL Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 576 amino acids |
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| COIL-2231H | Recombinant Human COIL Protein (Ser319-Glu538), N-His tagged | E.coli | Human | His | Ser319-Glu538 |
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| COIL-2746H | Recombinant Human COIL protein(131-240 aa), C-His-tagged | E.coli | Human | His | 131-240 aa |
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| COIL-783R | Recombinant Rhesus Macaque COIL Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| COIL-783R-B | Recombinant Rhesus Macaque COIL Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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Involved Pathway
COIL involved in several pathways and played different roles in them. We selected most pathways COIL participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with COIL were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
COIL has several biochemical functions, for example, disulfide oxidoreductase activity,identical protein binding,protein C-terminus binding. Some of the functions are cooperated with other proteins, some of the functions could acted by COIL itself. We selected most functions COIL had, and list some proteins which have the same functions with COIL. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein C-terminus binding | TBL1X,YAP1,PRDX3,IFT52,AGO2,VPS4B,DLG1,NEIL1,TNNI3K,YWHAQ |
| disulfide oxidoreductase activity | GRX2,TXN,TMX1,TXNL1,DNAJC10,PDIA3,PDIA2 |
| identical protein binding | NCL,G6PDX,SOD1,P2RX6,NUDT16,DLC,VWF,APAF1,CREBZF,PAK2 |
| protein binding | STRADA,DUSP13,INMT,ADORA1,ADAR,DEAF1,RAD23B,DCUN1D1,MTMR6,PFDN2 |
Interacting Protein
COIL has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with COIL here. Most of them are supplied by our site. Hope this information will be useful for your research of COIL.
VRK1;BYSL;XRCC5
Resources
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References
- Chung, J; Kang, JS; et al. Fast and continuous microorganism detection using aptamer-conjugated fluorescent nanoparticles on an optofluidic platform. BIOSENSORS & BIOELECTRONICS 67:303-308(2015).
- Kuttel, MM; Jackson, GE; et al. Capsular polysaccharide conformations in pneumococcal serotypes 19F and 19A. CARBOHYDRATE RESEARCH 406:27-33(2015).
