CLEC6A
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Official Full Name
C-type lectin domain family 6, member A -
Overview
Like dectin-1 (CLEC7A; MIM 606264), CLEC6A, or dectin-2, is a type II membrane receptor with an extracellular C-type lectin-like domain fold. However, unlike dectin-1, dectin-2 lacks an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain (Kanazawa et al., 2004 -
Synonyms
CLEC6A;C-type lectin domain family 6, member A;C type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 10 , CLECSF10;C-type lectin domain family 6 member A;dectin 2;C type lectin domain family 6 member A;C type lectin superfamily member 10;C-type lectin superfamily member 10;CLC6A_HUMAN;CLEC4N;CLECSF10;DC associated C type lectin 2;DC-associated C-type lectin 2;Dectin-2;Dectin2;Dendritic cell associated lectin 2;Dendritic cell-associated C-type lectin 2;OTTHUMP00000239172;C-type (calcium dependent, carbohydrate-recognition domain) lectin, sup
Recombinant Proteins
- Human
- Rhesus macaque
- Rat
- HEK293
- Mammalian Cell
- Human Cell
- Mouse myeloma cell line
- E.coli expression system
- Fc
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CLEC6A-8528H | Recombinant Human CLEC6A protein, hFc-tagged | HEK293 | Human | Fc | Thr42-Leu209 |
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| CLEC6A-906R | Recombinant Rhesus monkey CLEC6A Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| CLEC6A-1290HCL | Recombinant Human CLEC6A cell lysate | Human Cell | Human | Non |
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| CLEC6A-13H | Recombinant Human CLEC6A Protein, Thr46-Leu209, N-6×His tagged | Mouse myeloma cell line | Human | His | Thr46-Leu209 |
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| CLEC6A-731R | Recombinant Rhesus Macaque CLEC6A Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| CLEC6A-731R-B | Recombinant Rhesus Macaque CLEC6A Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| CLEC6A-8529H | Recombinant Human CLEC6A protein, His-tagged | HEK293 | Human | His | Thr42-Leu209 |
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| RFL28685RF | Recombinant Full Length Rat C-Type Lectin Domain Family 6 Member A(Clec6A) Protein, His-Tagged | E.coli expression system | Rat | His | Full L. Full Length (1-209) |
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Involved Pathway
CLEC6A involved in several pathways and played different roles in them. We selected most pathways CLEC6A participated on our site, such as C-type lectin receptors (CLRs),Dectin-2 family,Immune System, which may be useful for your reference. Also, other proteins which involved in the same pathway with CLEC6A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Innate Immune System | TXNIP,LGALS3,IRAK3,SIGLEC15,PANX1,BTR22,DDX41,BFB,CFHL1,RIPK3 |
| C-type lectin receptors (CLRs) | UBE2V1,AHCYL1,CLEC4D,CASP8L1,MALT1,CLEC4A,ITPR2,IL1B2,TAB1,CREBBP |
| Dectin-2 family | CLEC4D,CLEC4A |
| Immune System | SIGLEC11,GBP2,BLMH,GHRB,RNF138,IFIT3,KIR2DS2,KPNA3,C1rb,B2ML |
Protein Function
CLEC6A has several biochemical functions, for example, carbohydrate binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CLEC6A itself. We selected most functions CLEC6A had, and list some proteins which have the same functions with CLEC6A. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| carbohydrate binding | CLEC4A,MBL1,REG3A,CHODL,CD69,CLEC10A,HBL4,KLRB1A,GALNT12,EMC7 |
Interacting Protein
CLEC6A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CLEC6A here. Most of them are supplied by our site. Hope this information will be useful for your research of CLEC6A.
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