Cldn18
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Official Full Name
claudin 18
Recombinant Proteins
- Human
- Mouse
- Cynomolgus
- Macaca fascicularis
- Mus musculus
- Bovine
- HEK293
- Insect Cells
- Wheat Germ
- Mammalian Cells
- E.coli
- In Vitro Cell Free System
- Non
- Flag
- His
- His&Twin Strep
- GST
- His&SUMO
- mCherry
- GFP
- His&Avi
- His&Fc&Avi
- Strep&Flag
Involved Pathway
Cldn18 involved in several pathways and played different roles in them. We selected most pathways Cldn18 participated on our site, such as Cell adhesion molecules (CAMs),Tight junction,Leukocyte transendothelial migration, which may be useful for your reference. Also, other proteins which involved in the same pathway with Cldn18 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Hepatitis C | CLDN23,IFNA16,TP53,PIK3CD,AKT2,RNASEL,IFNA14,CLDN20,MAPK1,ARAF |
| Leukocyte transendothelial migration | VASP,CXCL12,CLDN16,RASSF5,JAM2,VAV3,ARHGAP35,BCAR1,F11R,CLDN5 |
| Tight junction | VAPAL,PRKCBB,F11R,CDC42,ACTB1,CASK,MYL9A,CLDN15A,EPB41L3,INADL |
| Cell adhesion molecules (CAMs) | HLA-E,CADM3,CNTNAP1,NRXN3,NLGN3A,NRXN2A,NRXN1,PECAM1,ITGB7,HLA-DQB1 |
Protein Function
Cldn18 has several biochemical functions, for example, protein binding,structural molecule activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Cldn18 itself. We selected most functions Cldn18 had, and list some proteins which have the same functions with Cldn18. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| structural molecule activity | SEMG2,SEPT5,COL15A1,MPZ,CLDND,PGM5,MAP1B,CLDN23,TUBG2,SEPT7 |
| protein binding | RUNX1T1,ZNF843,IFNAR2,SRP14,TXNRD1,MUL1,ZWILCH,KRT81,NPPB,KRT79 |
Interacting Protein
Cldn18 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Cldn18 here. Most of them are supplied by our site. Hope this information will be useful for your research of Cldn18.
Ywhae
Resources
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References
- Woll, S; Schlitter, AM; et al. Claudin 18.2 is a target for IMAB362 antibody in pancreatic neoplasms. INTERNATIONAL JOURNAL OF CANCER 134:731-739(2014).
- Micke, P; Mattsson, JSM; et al. Aberrantly activated claudin 6 and 18.2 as potential therapy targets in non-small-cell lung cancer. INTERNATIONAL JOURNAL OF CANCER 135:2206-2214(2014).
