CHRNA1
-
Official Full Name
cholinergic receptor, nicotinic, alpha 1 (muscle) -
Overview
The muscle acetylcholine receptor consiststs of 5 subunits of 4 different types: 2 alpha isoforms and 1 each of beta, gamma, and delta subunits.2 This gene encodes an alpha subunit that plays a role in acetlycholine binding/channel gating. Alternatively -
Synonyms
CHRNA1;cholinergic receptor, nicotinic, alpha 1 (muscle);cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle) , CHRNA;acetylcholine receptor subunit alpha;acetylcholine receptor;nicotinic;alpha 1 (muscle);nicotinic cholinergic receptor alp
Recombinant Proteins
- Human
- Rat
- Mouse
- Chicken
- Zebrafish
- Pacific electric ray
- Torpedo californica
- Tetronarce Californica
- Torpedo Californica
- Wheat Germ
- E.coli
- Mammalian Cell
- E.Coli or Yeast
- HEK293
- Insect Cell
- Yeast
- E. coli
- In Vitro Cell Free System
- Insect cells
- GST
- His
- Non
- His&T7
- His&Fc&Avi
- His&Trx
- His&SUMO
- N-His&C-Myc
- His&PDI
Involved Pathway
CHRNA1 involved in several pathways and played different roles in them. We selected most pathways CHRNA1 participated on our site, such as Acetylcholine Binding And Downstream Events,Activation of Nicotinic Acetylcholine Receptors,Effects of Botulinum toxin, which may be useful for your reference. Also, other proteins which involved in the same pathway with CHRNA1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Highly calcium permeable nicotinic acetylcholine receptors | CHRNB4,CHRNA3,CHRNA5,CHRNB2,CHRNA2,CHRNA4 |
| Acetylcholine Binding And Downstream Events | CHRNB4,CHRNA5,CHRNE,CHRNB2,CHRNA3,CHRNA4,CHRNA2,CHRNA7,CHRND |
| ErbB2/ErbB3 signaling events | RNF41,CHRNE,DOCK7,FMNL3 |
| Highly calcium permeable postsynaptic nicotinic acetylcholine receptors | CHRNA7,CHRNA5,CHRNA2,CHRNB4,CHRNA4,CHRNB2,CHRNA3 |
| Neuronal System | KCNQ2A,SYT1A,UNC13B,SLC6A1B,KCNAB1,KCNV1,KCNK2,AKAP5,CACFD1,PICK1 |
| Effects of Botulinum toxin | UNC13B,RAB3GAP2,CCDC167 |
| Neuroactive ligand-receptor interaction | MCHR2,GRIN2B,DRD2B,GABBR1,GLRBB,PRLR,GLRA3,C5AR1,PPYR1,MLNR |
| Activation of Nicotinic Acetylcholine Receptors | CHRNB4,CHRNA4,CHRNB2,CHRNA2,CHRNA5,CHRND,CHRNE,CHRNA7,CHRNA3 |
Protein Function
CHRNA1 has several biochemical functions, for example, contributes_to acetylcholine binding,contributes_to acetylcholine receptor activity,acetylcholine-activated cation-selective channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CHRNA1 itself. We selected most functions CHRNA1 had, and list some proteins which have the same functions with CHRNA1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| contributes_to acetylcholine-activated cation-selective channel activity | CHRNA10A,CHRNB1,CHRNA4B,CHRFAM7A,CHRNA2A,CHRNB3A,CHRNB1L,CHRNA10,CHRNB3B,ZACN |
| ion channel activity | CNGA5,TPCN1,KCNC2,TRPM1,DDX1,TRPC7B,CLCN6,TRPV5,SCN11A,TRPN1 |
| contributes_to acetylcholine receptor activity | CHRNA4B,CHRNB1L,CHRNA2A,CHRNA10A,CHRND,CHRNB1,CHRNB3A,CHRNB3B,CHRNA9,ZACN |
| contributes_to acetylcholine binding | CHRNA2A,CHRNA10,CHRNB1,CHRNB4,CHRNA2,CHRNB1L,CHRNA4B,CHRNA10A,CHRNB3B,CHRNA3 |
| acetylcholine-activated cation-selective channel activity | CHRNB2,CHRNA4B,CHRNB1L,Chrng,CHRNB3A,CHRNA2,CHRNA10A,CHRNB3,CHRNA3,CHRNA4 |
Interacting Protein
CHRNA1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CHRNA1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CHRNA1.
CHRNB1;CHRNG;chrnd
Resources
Related Services
Related Products
References
