CHL1
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Official Full Name
cell adhesion molecule with homology to L1CAM -
Overview
The protein encoded by this gene is a member of the L1 gene family of neural cell adhesion molecules. It is a neural recognition molecule that may be involved in signal transduction pathways. The deletion of one copy of this gene may be responsible for m -
Synonyms
CHL1;cell adhesion molecule with homology to L1CAM;neural cell adhesion molecule L1-like protein;CALL;Cell adhesion molecule with homology to L1CAM (close homolog of L1);Cell adhesion molecule with homology to L1CAM (close homologue of L1);Close homolog of L1;FLJ44930;L1 cell adhesion molecule 2;L1CAM2;MGC132578;Neural cell adhesion molecule;chl1-like protein;LICAM2;AI465420;A530023M13Rik
Recombinant Proteins
- Human
- Mouse
- HEK293
- E.coli
- Mammalian Cells
- Wheat Germ
- Human Cells
- Mouse
- His
- GST
- Non
- His&T7
- His&Fc&Avi
- Fc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CHL1-3145H | Recombinant Human CHL1 protein, His-tagged | HEK293 | Human | His | Met1-Gln1080 | |
| CHL1-3833H | Recombinant Human CHL1 protein, His-tagged | E.coli | Human | His | 737-1066 aa | |
| Chl1-455M |
Active Recombinant Mouse Chl1, His-tagged
|
Mammalian Cells | Mouse | His | 25-1043;227-242 a.a. |
|
| CHL1-1244H | Recombinant Human CHL1 Protein, GST-Tagged | Wheat Germ | Human | GST |
|
|
| CHL1-220M | Recombinant Mouse Chl1, Fc tagged | Human Cells | Mouse | His | 1-1027 a.a. |
|
| CHL1-260M | Recombinant Mouse Chl1, His tagged | Human Cells | Mouse | His | 1-1027 a.a. |
|
| Chl1-489M | Recombinant Mouse Chl1 | Human Cells | Mouse | Non | Met1-Gln1027 |
|
| CHL1-001MCL | Recombinant Mouse CHL1 cell lysate | Human Cells | Mouse | Non |
|
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| CHL1-2202HCL | Recombinant Human CHL1 cell lysate | Human Cells | Human | Non |
|
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| CAB11511MH | Mouse Anti-Human Cell Adhesion Molecule With Homology to L1CAM Monoclonal Antibody | Mouse | Human | Non |
|
|
| CHL1-1527H | Recombinant Human CHL1 protein, His & T7-tagged | E.coli | Human | His&T7 | Pro35~Glu328 |
|
| Chl1-1646M | Recombinant Mouse Chl1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
|
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| Chl1-1646M-B | Recombinant Mouse Chl1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
|
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| CHL1-1703H | Recombinant Human CHL1 Protein (Pro35-Glu328), N-His tagged | E.coli | Human | His | Pro35-Glu328 |
|
| CHL1-1975M | Recombinant Mouse CHL1 protein, hFc-tagged | HEK293 | Mouse | Fc | Met1-Gln1027 |
|
Involved Pathway
CHL1 involved in several pathways and played different roles in them. We selected most pathways CHL1 participated on our site, such as Axon guidance,CHL1 interactions,Developmental Biology, which may be useful for your reference. Also, other proteins which involved in the same pathway with CHL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| CHL1 interactions | CNTN6 |
| Axon guidance | RASGRP4,TRPC3,EFNA5,DUSP7,PPP3CC,FGF18B,SPRED3,ACTR3,LAMTOR2,SLC14A2 |
| L1CAM interactions | DPYSL2B,CD24,SCN4A,KIF4,NADL1.1,SCN3B,NRP2,SCN2B,SCN2A,SCN9A |
| Developmental Biology | COL4A4,RND1L,CSNK2A2,INSM1B,PAQR3A,PAK4,FOXH1,DUSP5,NRG4,FGFR1B |
Protein Function
CHL1 has several biochemical functions, for example, protease binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CHL1 itself. We selected most functions CHL1 had, and list some proteins which have the same functions with CHL1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protease binding | TYSND1,HSPA6,FN1,ELANE,SERPINE1,POLG,INSL3,DVL3,LCN2,STIM1 |
Interacting Protein
CHL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CHL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CHL1.
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References
- Katic, J; Loers, G; et al. Interaction of the Cell Adhesion Molecule CHL1 with Vitronectin, Integrins, and the Plasminogen Activator Inhibitor-2 Promotes CHL1-Induced Neurite Outgrowth and Neuronal Migration. JOURNAL OF NEUROSCIENCE 34:14606-14623(2014).
- Marko, NF; Coughlan, C; et al. Towards an integrated molecular and clinical strategy to predict early recurrence in surgically resected non-functional pituitary adenomas. JOURNAL OF CLINICAL NEUROSCIENCE 19:1535-1540(2012).
