CERS5
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Official Full Name
ceramide synthase 5 -
Synonyms
CERS5;ceramide synthase 5;LAG1 homolog, ceramide synthase 5 , LAG1 longevity assurance homolog 5 (S. cerevisiae) , LASS5;FLJ25304;MGC45411;Trh4;LAG1 homolog, ceramide synthase 5;LAG1 longevity assurance homolog 5;LASS5
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CERS5-10029Z | Recombinant Zebrafish CERS5 | Mammalian Cells | Zebrafish | His |
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| CERS5-1400H | Recombinant Human CERS5 | Mammalian Cells | Human | His |
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| CERS5-2659H | Recombinant Human CERS5 Protein, His (Fc)-Avi-tagged | HEK293 | Human | His&Fc&Avi |
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| CERS5-2659H-B | Recombinant Human CERS5 Protein Pre-coupled Magnetic Beads | HEK293 | Human |
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| RFL16061MF | Recombinant Full Length Mouse Ceramide Synthase 5(Cers5) Protein, His-Tagged | E.coli | Mus musculus | His | Full L. Full Length (1-414) |
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| RFL7254HF | Recombinant Full Length Human Ceramide Synthase 5(Cers5) Protein, His-Tagged | E.coli | Human | His | Full L. Full Length (1-392) |
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Involved Pathway
CERS5 involved in several pathways and played different roles in them. We selected most pathways CERS5 participated on our site, such as Metabolic pathways,Metabolism,Metabolism of lipids and lipoproteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with CERS5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolism of lipids and lipoproteins | PIK3R6,SLC25A20,CDS1,MED26,BCHE,DECR1,FABP11A,ELOVL1A,CEPT1,MED8 |
| Sphingolipid signaling pathway | GNAI2,PPP2R1B,DEGS2,RAF1,PRKCA,SPHK1,RHOA,TRP53,GNAI3,ASAH2 |
| Sphingolipid de novo biosynthesis | CERS4A,OSBP,PPM1LA,FA2H,PPM1L,PPM1LB,ACER1,COL4A3BP,VAPB,SGMS2 |
| Metabolism | COQ6,HPSE,CIAPIN1,KCNS3,BCKDK,PFKLB,SLC2A3,PPARGC1B,SLC44A5B,FABP11B |
| Sphingolipid metabolism | SGMS2,GLTP,NEU3.5,NEU1,CERS1,GDF1,ARSF,NEU3.1,DEGS1,ASAH1B |
| Metabolic pathways | HK2,CDA,CHSY3,ASAH1,UGT1A6B,ATP6V1C1,UROD,SPTLC2,COASY,IDS |
Protein Function
CERS5 has several biochemical functions, for example, DNA binding,sphingosine N-acyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CERS5 itself. We selected most functions CERS5 had, and list some proteins which have the same functions with CERS5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| DNA binding | DMRT2,ZNF45,FOXF1,CRSP7,TBX5,PBX1A,IRX3B,EBF2,ZNF497,ZBTB8A |
| sphingosine N-acyltransferase activity | LASS2,CERS4,CERS2A,CERS3B,CERS2,LASS1,LASS5,CERS4A,LASS4,FAM57B |
Interacting Protein
CERS5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CERS5 here. Most of them are supplied by our site. Hope this information will be useful for your research of CERS5.
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References
- Haller, JF; Cavallaro, P; et al. Endogenous beta-glucocerebrosidase activity in Abca12(-/-) epidermis elevates ceramide levels after topical lipid application but does not restore barrier function. JOURNAL OF LIPID RESEARCH 55:493-503(2014).
- Kamani, M; Mylvaganam, M; et al. Adamantyl Glycosphingolipids Provide a New Approach to the Selective Regulation of Cellular Glycosphingolipid Metabolism. JOURNAL OF BIOLOGICAL CHEMISTRY 286:21413-21426(2011).
